Inflammatory effects of periodontally diseased cementum studied by autogenous dental root implants in humans

Journal of Periodontology
N J LópezR de la Sotta

Abstract

The inflammatory potential of diseased cementum was studied by implanting 70 autogenous fragments from periodontally involved roots into the mucosa of 56 patients. The implants were divided into groups depending upon the type of preparation the root received prior to implantation. Fifteen healthy root fragments implanted into 15 patients served as controls. Histologic results showed that implanted fragments from roots that had been scaled caused the most response with acute inflammation up to 14 days and chronic inflammation to 21 days. In cases in which these fragments were autoclaved the acute inflammation was not as severe. In the cases in which the roots were planed and autoclaved, even less acute inflammation was seen in the 7-day specimens while some chronic inflammation persisted in the 21-day specimens. Implants from healthy roots evoked no response. The inflammation caused by the autoclaved diseased cementum was attributed to thermo-stable endotoxin. It was concluded that in advanced periodontal disease it is necessary to remove all of the cementum exposed to the pocket to eliminate its potential for inducing inflammation.

References

Nov 1, 1975·Journal of Periodontology·J J AleoP A Farber
Dec 1, 1966·Archives of Oral Biology·W B Hall
Jun 30, 1966·Annals of the New York Academy of Sciences·Y B Kim, D W Watson
Jan 1, 1966·Journal of Periodontal Research·E TheiladeH Löe
May 1, 1972·Journal of Periodontology·J SchwartzR B Parker
Sep 1, 1974·Journal of Periodontology·J J AleoA P Varboncoeur
Oct 1, 1972·Journal of Periodontology·L ShapiroR E Stallard
Mar 1, 1971·Journal of Dental Research· LöH
Jun 30, 1966·Annals of the New York Academy of Sciences·S E MergenhagenK C Hsu
Apr 1, 1971·Archives of Oral Biology·C G Hatfield, A Baumhammers
Jan 1, 1954·Annual Review of Physiology·L THOMAS
May 1, 1961·The Journal of Infectious Diseases·S E MERGENHAGENH W SCHERP

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Citations

Jun 1, 1982·Journal of Periodontology·N M NakibS N Goldstine
Nov 1, 1985·Journal of Periodontology·M L Morris
Aug 1, 1986·Journal of Periodontology·A D SteinbergJ Lipowski
Mar 1, 1983·Journal of Clinical Periodontology·S LindskogL Hammarström
Nov 1, 1982·Journal of Clinical Periodontology·M P Proye, A M Polson
Jan 1, 1992·Journal of Periodontology·A D SteinbergG LeBreton
Dec 1, 1994·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·F GagnonG S Schuster

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