Inflammatory myofibroblastic tumor of the liver: A case report and review of literature

World Journal of Hepatology
Alexandra FilipsAnja Lachenmayer

Abstract

Inflammatory myofibroblastic tumors of the liver (IMTL) are extremely rare neoplasms and very little is known about their clinical presentation, pathogenesis, and biological behavior. Due to their absolute rarity, it is almost impossible to obtain a definite diagnosis without histological examination. Because of their intermediate biological behavior with the risk for local recurrence and metastases, surgical resection is recommend whenever IMTL is suspect. We herein present a case of an otherwise healthy 32-year-old woman who presented with intermittent fever, unclear anemia, malaise and right flank pain 4 mo postpartum. The liver mass in segment IVa/b was highly FDG avid in the positron emission tomography-computed tomography. Hepatic resection was performed achieving a negative resection margin and an immediate resolution of all clinical symptoms. Histological analysis diagnosed the rare finding of an inflammatory myofibroblastic tumor of the liver and revealed cytoplasmic anaplastic lymphoma kinase expression by immunohistochemistry. Twelve months follow-up magnetic resonance imaging showed no recurrence and no metastases in the fully recovered patient. IMTLs are extremely rare and difficult to diagnose. Due to their interm...Continue Reading

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Citations

Jul 6, 2021·Journal of Clinical Imaging Science·Mohamed Tarek El-DiastyAhmed Haitham Abduljabbar

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Methods Mentioned

BETA
surgical resection
biopsy

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