PMID: 15365413Sep 15, 2004Paper

Inflammatory pseudotumor of the liver associated with Crohn's disease

Journal of Clinical Gastroenterology
Georgios I PapachristouScott E Plevy

Abstract

Inflammatory pseudotumor (IPT) of the liver is a rare, benign lesion that is characterized by proliferating fibrous tissue infiltrated by inflammatory cells. The exact etiology of IPT remains unclear. Although the association of IPT with systemic inflammatory disorders has been established, a specific link with Crohn's disease is rare. We report two cases of IPT associated with Crohn's disease. Both patients were elderly males who presented with abdominal pain and jaundice. At the time of presentation, both had active Crohn's disease that was undiagnosed. Computed tomography demonstrated a liver mass, and endoscopic retrograde cholangiography revealed biliary strictures in both patients. Given their symptomatic jaundice and concern for cholangiocarcinoma, they underwent abdominal surgical exploration and pathology results revealed IPT. They were subsequently diagnosed with Crohn's disease. Following treatment of Crohn's disease, there was significant improvement in their overall clinical status. An underlying diagnosis of inflammatory bowel disease should be considered in patients with IPT.

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Citations

Aug 1, 2007·Arthritis and Rheumatism·Cesar Díaz-TornéJosé Valverde
Dec 1, 2007·European Journal of Gastroenterology & Hepatology·Themistoklis VassiliadisNikolaos Evgenidis
Jan 25, 2011·World Journal of Surgical Oncology·Walid FarajMohamed Khalife
Sep 15, 2011·European Journal of Gastroenterology & Hepatology·Dávid SemjénTamás Tornóczky
Jun 12, 2012·Renal Failure·Yong-Heng HuangYun-Le Wan
Mar 14, 2007·European Journal of Gastroenterology & Hepatology·Moinuddin M HooseinBrian R Davidson
Nov 2, 2016·BJR Case Reports·Frans van TonderTom Sutherland
May 21, 2013·Journal of the Chinese Medical Association : JCMA·Chia-Bang ChenYao-Li Chen
Jun 21, 2020·Inflammatory Bowel Diseases·Eric SchaferGeorge Smallfield
Feb 15, 2014·World Journal of Clinical Cases·Yogesh PuriGiuseppe Kito Fusai

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