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Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

The New England Journal of Medicine

Nov 30, 2000

Peter E LipskyAnti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

Abstract

Neutralization of tumor necrosis factor a (TNF-alpha) for three to six months reduces the symptoms and signs of rheumatoid arthritis. However, the capacity of this approach to effect a more sustained benefit and its effect on joint damage are not known. We treated 428 patients who had a...read more

Mentioned in this Paper

Monoclonal Antibodies
Necrosis
Antirheumatic Drugs, Disease-Modifying
Tumor Necrosis Factor-alpha
Intravenous Injections
Chimera Organism
Weighing Patient
Polychemotherapy
TNF
Joints
197
1
Paper Details
References
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  • Citations1369
123
  • References28
  • Citations1369
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Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

The New England Journal of Medicine

Nov 30, 2000

Peter E LipskyAnti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

PMID: 11096166

DOI: 10.1056/nejm200011303432202

Abstract

Neutralization of tumor necrosis factor a (TNF-alpha) for three to six months reduces the symptoms and signs of rheumatoid arthritis. However, the capacity of this approach to effect a more sustained benefit and its effect on joint damage are not known. We treated 428 patients who had a...read more

Mentioned in this Paper

Monoclonal Antibodies
Necrosis
Antirheumatic Drugs, Disease-Modifying
Tumor Necrosis Factor-alpha
Intravenous Injections
Chimera Organism
Weighing Patient
Polychemotherapy
TNF
Joints
197
1

Similar Papers Found In These Feeds

General Medical Journal eTOCs

Discover the latest medical research in this collection of the top medical journals.

NEJM eTOC

The New England Journal of Medicine (NEJM) is a medical journal published by the Massachusetts Medical Society. Discover the latest research from NEJM here.

Related Papers

The New England Journal of Medicine

A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis

The New England Journal of MedicineNovember 30, 2000
Joan M BathonBarbara K Finck
Paper Details
References
  • References28
  • Citations1369
123
  • References28
  • Citations1369
12345...
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