Influence of 17beta-estradiol, progesterone, and dexamethasone on diapedesis and viability of bovine blood polymorphonuclear leukocytes

Journal of Dairy Science
I LamoteC Burvenich

Abstract

The aim of the current study was to investigate whether polymorphonuclear leukocyte (PMN) diapedesis and viability are influenced by steroid hormones. Using an in vitro model with different types of cell layers (bovine mammary epithelial cells and fibroblasts), we investigate whether steroid hormone treatments (17beta-estradiol, progesterone, and dexamethasone) have an influence on the diapedesis capacity and viability of PMN. In addition, we studied apoptosis of PMN in the in vitro model and evaluated the influence of different types of cell layers and steroid hormone treatments on this process. A significant decrease in the number of viable PMN in the lower compartment of the in vitro model (i.e., number of migrated PMN x viability after migration) was found after 17beta-estradiol treatment, whereas no influence was detected after progesterone or dexamethasone treatment. The effect of 17beta-estradiol was not due to a lower viability before migration as none of the treatments caused a significant effect on the viability before diapedesis. This treatment effect was not influenced by endogenous 17beta-estradiol or progesterone levels before isolation because there was no correlation between these plasma levels and PMN diapedesi...Continue Reading

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Citations

Sep 21, 2004·Journal of Dairy Science·E MonfardiniC Burvenich
Jul 25, 2008·Reproduction in Domestic Animals = Zuchthygiene·S Pyörälä
Jul 16, 2008·Archives of Histology and Cytology·Yoshihiro WakabayashiMitsuhiro Kawata
Nov 13, 2008·Reproduction in Domestic Animals = Zuchthygiene·A Chaveiro, F Moreira da Silva
Jun 16, 2010·Journal of Animal Physiology and Animal Nutrition·A PezeshkiC Burvenich
Feb 11, 2012·European Journal of Pain : EJP·K E Torres-ChávezC H Tambeli
Jun 18, 2020·Animals : an Open Access Journal From MDPI·Jonas Habel, Albert Sundrum
Feb 16, 2018·Cell and Tissue Research·Laura L Bassel, Jeff L Caswell
Jun 16, 2017·Veterinary Immunology and Immunopathology·Dan-Dan XuRui Wu
Jun 16, 2005·The Veterinary Clinics of North America. Food Animal Practice·Grant S Frazer

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