PMID: 16510927Mar 3, 2006Paper

Influence of 4-nitrophenol on some biochemical and morphological indices of rat blood

Georgian Medical News
B A ArzianiN I Kumsiashvili

Abstract

Influence of different doses of 4-nitrophenol on some biochemical and morphological indices of rat blood was studied. Glucose and beta-lipoprotein concentration increased, but total protein concentration decreased in response to intraperitoneal injection of xenobiotic. As a result of xenobiotic action, the total amount of leukocytes and thrombocytes increased, while the amount of erythrocytes decreased. The morphological study of structural indices of blood formed elements has demonstrated, that intensity of the defensive response of blood formed elements was 4-nitrophenol dose-dependent.

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