Influence of a beta2-agonist on physical performance at low temperature in elite athletes

Medicine and Science in Sports and Exercise
K LarssonP Ohlsén

Abstract

Beta2-agonists are frequently used by elite cross-country skiers, a group of athletes with a high prevalence of asthma. It has been claimed that beta2-agonists have a positive effect on physical performance. The aim of the present study was to investigate whether inhalation of a beta2-agonist increases physical performance at low temperature in healthy, nonasthmatic athletes with normal bronchial responsiveness. Twenty elite male athletes (cyclists, cross-country skiers, middle and long distance runners) with no history of allergy or airway disease and who had normal spirometry and methacholine bronchial provocation tests performed a maximal exercise test on a treadmill in a climate chamber at approximately 10 degrees C on two subsequent days. Before exercise they inhaled terbutaline (3 mg from MDI) or placebo in a randomized, single blind manner. After 10-min warm-up on the treadmill, a submaximal work preceded a stepwise increase of the workload until exhaustion. Lung function, ventilation, oxygen uptake, and heart rate were determined and blood samples for lactate and potassium analyses were drawn before, during, and after exercise. Terbutaline induced a significant bronchodilatation; FEV1 increased from 4.8 (4.4-5.1) L to 5...Continue Reading

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Citations

Dec 6, 2006·Medicine and Science in Sports and Exercise·Amund RiiserKai-Håkon Carlsen
May 27, 2008·British Journal of Pharmacology·E DavisR J Summers
Dec 21, 2007·Scandinavian Journal of Medicine & Science in Sports·V BackerL Pedersen
Nov 3, 2010·Fundamental & Clinical Pharmacology·Dimitrios D NikolopoulosStamatios E Theocharis
Oct 25, 2016·European Journal of Applied Physiology·Muath M AltarawnehMichael J McKenna
Jul 27, 2000·Medicine and Science in Sports and Exercise·M A van BaakF Hartgens
Jun 5, 2004·Medicine and Science in Sports and Exercise·Antti AlarantaIlkka Helenius
Oct 9, 2013·British Journal of Sports Medicine·Sarah KochMichael S Koehle
Feb 24, 2007·Scandinavian Journal of Medicine & Science in Sports·A TjørhomK H Carlsen
Jul 7, 2012·European Journal of Applied Physiology·Anthony M J SanchezRobin Candau
Jul 10, 2013·Scandinavian Journal of Medicine & Science in Sports·A KalsenV Backer
Feb 6, 2002·Medicine and Science in Sports and Exercise·Ian B StewartDonald C McKenzie
Jul 20, 2002·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·Donald C McKenzieKenneth D Fitch

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