Influence of administered indigenous microorganisms on uptake of [iodine-125] gamma-globulin in vivo by intestinal segments of neonatal calves

Journal of Dairy Science
R E JamesK A Cummins

Abstract

Ten calves less than 14 h of age (average 8.6 h) were anaesthetized, and the intestine was ligated into segments 10 cm in length at 3-cm intervals beginning 1.8 m anterior of the ileocecal junction and proceeding proximally. Seven treatments were assigned in random order to segments in three successive sections of the small intestine. Segments received 1 ml of viable bacteria of intestinal origin, autoclaved bacteria of intestinal origin, or sterile microbiological broth at zero time; then after 4 h they were injected with iodine-125 labeled gamma-globulin. After an additional 1.5 h, the experiment was ended and uptake assayed. Two treatments measured anaerobic microbial growth after 4 h incubation with 1 ml of either sterile broth or live bacteria culture. Residual [iodine-125] gamma-globulin was measured in segments receiving 1 ml of sterile broth or live bacteria culture with 5.5-h incubation followed by 15-s exposure to labeled gamma-globulin. Uptake was lowest in segments receiving live bacteria as compared to segments receiving sterile inocula. Number of bacteria per gram of tissue was correlated negatively with uptake. Low corticosteroids in serum were associated with low uptake of gamma-globulin.

References

Oct 1, 1978·Journal of Dairy Science·R E James, C E Polan
Sep 1, 1979·Journal of Dairy Science·R E JamesM L McGilliard
Sep 1, 1977·Journal of Dairy Science·L D CorleyE W Jones
Jan 1, 1965·Biologia Neonatorum. Neo-natal Studies·J G Lecce
Apr 1, 1970·The Journal of Nutrition·C W Broughton, J G Lecce
Oct 1, 1965·The Journal of Pathology and Bacteriology·H W Smith
Jul 1, 1973·Journal of Dairy Science·F C GwazdauskasC J Wilcox
Oct 1, 1965·Food and Cosmetics Toxicology·B L OserM Oser
Oct 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·G D Abrams, J E Bishop

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Citations

Feb 19, 2013·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Tomislav BedekovicZeljko Cac
Apr 3, 2018·Journal of Veterinary Emergency and Critical Care·Semih AltanMuharrem Erol
Oct 21, 2016·Journal of Dairy Science·A J PhippsM F Pyman
Nov 13, 1998·Journal of Dairy Science·J D Quigley, J J Drewry
Jul 27, 2015·Journal of Dairy Science·G AraujoA Bach
Jan 7, 2010·Journal of Animal Physiology and Animal Nutrition·E Ferdowsi NiaG R Ghorbani
Mar 30, 1999·The Proceedings of the Nutrition Society·H GrimmW Seeger
Aug 19, 2020·Journal of Animal Science·Adam J Geiger
Jun 21, 2013·Journal of Veterinary Internal Medicine·A-C BrisvilleL C Smith
Jul 14, 2021·Journal of Dairy Science·Soňa ŠlosárkováEliška Nejedlá

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