Influence of antimicrobial photodynamic therapy in carious lesion. Randomized split-mouth clinical trial in primary molars

Photodiagnosis and Photodynamic Therapy
Luísa Valente Gotardo Lara AlvesSilmara Aparecida Milori Corona

Abstract

The literature presents many studies regarding photodynamic antimicrobial therapy (aPDT). However, the great variety of protocols to be used can directly influence its effectiveness in reducing microorganisms. The aim of this randomized split-mouth clinical study was to evaluate the effect of aPDT in the reduction of Streptococcus mutans and their effect on restorations performed. Twenty children between 6 and 8 years old with active caries and dentin cavitation, located on the occlusal surface of homologous primary molars were included. The selective removal of carious tissue was performed in both molars, than one was subsequently restored and the other received aPDT treatment on the affected dentin with low intensity laser (InGaAlP) associated to 0.005% methylene blue photosensitizer before restoration. Dentin collections were performed only in the tooth submitted to aPDT in three moments: before and after selective caries removal and after application of aPDT. The restorations were analyzed after polishing and after 6 months using United States Public Health Service (USPHS) method. Data were analyzed using ANOVA with repeated measures and Bonferroni post-hoc test with a significance level of 5%. There was a significant reduc...Continue Reading

Citations

Jul 26, 2019·International Journal of Molecular Sciences·Analú Barros de OliveiraCarla Raquel Fontana
Aug 8, 2020·Photobiomodulation, Photomedicine, and Laser Surgery·Leticia Martins PereiraSérgio Luiz Pinheiro
Mar 17, 2020·Photodiagnosis and Photodynamic Therapy·Leonardo Lobo Ribeiro CavalcanteSilmara Aparecida Milori Corona
Jan 12, 2021·Journal of Lasers in Medical Sciences·Armin MirfasihiMaziar Mir
Mar 23, 2020·Photodiagnosis and Photodynamic Therapy·Ampika Phutim MangkhalthonTeerasak Damrongrungruang
Jan 28, 2022·Dental Materials Journal·Zhang HongboHidehiko Sano

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