Abstract
This study sought to ascertain whether patients with a bicuspid aortic valve (BAV) have an intrinsic alteration in regional aortic stiffness compared with patients with tricuspid aortic valve (TAV) and Marfan syndrome (MFS) patients with similar aortic sizes, as well as to assess the influence of ascending aorta (AAo) dilation on regional stiffness parameters in BAV patients. Imaging biomarkers as predictors of BAV, MFS, and degenerative AAo aneurysms in TAV patients (DA-TAV) are lacking. Biomechanical characterization has been proposed as a possible tool for further aneurysm stratification. A total 234 subjects (136 BAV, 44 MFS, and 18 DA-TAV patients and 36 healthy control subjects) were included. The cardiac magnetic resonance protocol comprised 4-dimensional flow to assess AAo and descending aorta (DAo) pulse wave velocities (PWVs) and double-oblique, 2-dimensional, steady-state free-precession cine cardiac magnetic resonance to compute aortic distensibility (AD). On adjusted analysis, nondilated BAV patients had similar PWV and AD as healthy control subjects in both AAo and DAo, whereas dilated BAV did not differ from DA-TAV. In contrast, AAo and DAo stiffness in MFS patients was markedly greater than in BAV patients, incr...Continue Reading
Citations
Mar 29, 2019·European Heart Journal Cardiovascular Imaging·Lydia Dux-SantoyJosé F Rodríguez-Palomares
Oct 1, 2019·Journal of Hypertension·Gilles SoulatElie Mousseaux
Mar 11, 2020·Annual Review of Biomedical Engineering·Gilles SoulatMichael Markl
Sep 2, 2020·European Radiology·Judy Rizk
Apr 27, 2019·Frontiers in Physiology·Guillaume GoudotEmmanuel Messas
Oct 15, 2019·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·A GualaJ Rodriguez-Palomares
Apr 8, 2020·Royal Society Open Science·R PonsJ Martorell
Feb 15, 2019·Frontiers in Physiology·Tianshu LiuJing Wang
Dec 12, 2019·Frontiers in Cardiovascular Medicine·Rachel E ClimieRosa Maria Bruno
Dec 6, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Lydia Dux-SantoyJosé F Rodríguez-Palomares
Mar 27, 2020·Arteriosclerosis, Thrombosis, and Vascular Biology·Lydia Dux-SantoyJosé F Rodríguez-Palomares
Dec 2, 2020·International Journal of Cardiology·Ariel F PascanerEmilie Bollache
Mar 13, 2021·Journal of Hypertension·Francesco ToselloAlberto Milan
Feb 11, 2021·Physiological Measurement·M E CasciaroD Craiem
May 5, 2021·Expert Review of Cardiovascular Therapy·Mitsunobu KitamuraMohamed Abdel-Wahab
May 13, 2021·European Radiology·Andrea GualaJose F Rodríguez-Palomares
Jun 10, 2021·European Heart Journal Cardiovascular Imaging·Aroa Ruiz-MuñozGisela Teixido-Tura
Jun 6, 2020·Journal of the American College of Cardiology·Raymond Y KwongUNKNOWN JACC: Cardiovascular Imaging
Jun 15, 2021·Frontiers in Physiology·Stefan MöstlJens Tank
Jun 19, 2021·Journal of the American College of Cardiology·Angela Lopez-SainzGisela Teixido-Tura
Sep 10, 2021·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Kenichiro TakahashiShinichiro Kumita
Oct 17, 2021·European Radiology·Lydia Dux-SantoyAndrea Guala
Dec 8, 2021·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Konstantinos SpanosTilo Kölbel