Influence of baseline left ventricular function on the clinical outcome of surgical ventricular reconstruction in patients with ischaemic cardiomyopathy.

European Heart Journal
Jae K OhSTICH Investigators

Abstract

The Surgical Treatment for Ischemic Heart Failure (STICH) trial demonstrated no overall benefit when surgical ventricular reconstruction (SVR) was added to coronary artery bypass grafting (CABG) in patients with ischaemic cardiomyopathy. The present analysis was to determine whether, based on baseline left ventricular (LV) function parameters, any subgroups could be identified that benefited from SVR. Among the 1000 patients enrolled, Core Lab measures of baseline LV function with adequate quality were obtained in 710 patients using echocardiography, in 352 using cardiovascular magnetic resonance, and in 344 using radionuclide imaging. The relationship between LV end-systolic volume index (ESVI), end-diastolic volume index, ejection fraction (EF), regional wall motion abnormalities, and outcome were first assessed only by echocardiographic measures, and then by 13 algorithms using a different hierarchy of imaging modalities and their quality. The median ESVI and EF were 78.0 (range: 22.8-283.8) mL/m2 and 28.0%, respectively. Hazard ratios comparing the randomized arms by subgroups of LVESVI and LVEF measured by echocardiography found that patients with smaller ventricles (LVESVI <60 mL/m2) and better LVEF (≥33%) may have benefi...Continue Reading

References

Feb 1, 1989·The Thoracic and Cardiovascular Surgeon·V DorF Montiglio
Jul 4, 2001·Revista Portuguesa De Cardiologia : Orgão Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology·P Pinho
Aug 13, 2003·Circulation·Gerald M PohostMark Doyle
Jun 3, 2004·The Journal of Thoracic and Cardiovascular Surgery·Marco CirilloEugenio Quaini
Jun 30, 2004·The Journal of Thoracic and Cardiovascular Surgery·Lynda L MickleboroughSusan Carson
Jul 31, 2007·The Journal of Thoracic and Cardiovascular Surgery·Lorenzo MenicantiMarisa Di Donato
Nov 21, 2007·The Journal of Thoracic and Cardiovascular Surgery·Eric J VelazquezUNKNOWN STICH Investigators
Nov 21, 2007·The Journal of Thoracic and Cardiovascular Surgery·Marisa Di DonatoLorenzo Menicanti
Jan 24, 2009·The Annals of Thoracic Surgery·Marisa Di DonatoLorenzo Menicanti
Mar 31, 2009·The New England Journal of Medicine·Robert H JonesUNKNOWN STICH Hypothesis 2 Investigators
Jan 15, 2011·JACC. Cardiovascular Imaging·Marvin A KonstamJames E Udelson

❮ Previous
Next ❯

Citations

Jan 5, 2014·European Heart Journal·Georg Ertl, Frank Ruschitzka
Sep 11, 2013·Current Treatment Options in Cardiovascular Medicine·Robert Michler
Jun 19, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Kevin C Allman
Jun 16, 2015·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Minoru YoshidaTadashi Isomura
Feb 4, 2014·The Canadian Journal of Cardiology·Jean L Rouleau, Robert O Bonow
Nov 1, 2012·The Journal of Thoracic and Cardiovascular Surgery·Robert E MichlerUNKNOWN STICH Trial Investigators
Sep 5, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Stephan WindeckerAdam Witkowski
Feb 14, 2015·Journal of the American College of Cardiology·Eric J Velazquez, Robert O Bonow
Sep 14, 2015·JACC. Cardiovascular Imaging·Robert O BonowUNKNOWN STICH Trial Investigators
Aug 12, 2014·Journal of the American College of Cardiology·Julio A PanzaJean L Rouleau
Dec 3, 2014·The Journal of Thoracic and Cardiovascular Surgery·Tomasz KukulskiUNKNOWN Surgical Treatment for Ischemic Heart Failure Investigators
May 17, 2014·Heart Failure Reviews·Constantine L Athanasuleas, Gerald Buckberg
Oct 19, 2016·The Journal of Thoracic and Cardiovascular Surgery·Lotte E CouperusSaskia L M A Beeres
May 19, 2017·World Journal of Cardiology·Batric PopovicJean Pierre Villemot
Aug 3, 2019·Journal of Cardiac Surgery·Ali Fatehi HassanabadImtiaz Ali
Aug 3, 2019·Journal of the Saudi Heart Association·Waleed AlHabeebWalid Hassan
Apr 10, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Roman PfisterUNKNOWN Working Group of Interventional Cardiology of the German Society of Cardiology
May 23, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sachiko YamazakiHitoshi Yaku
Aug 31, 2018·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Miguel Sousa-UvaUNKNOWN ESC Scientific Document Group
Aug 31, 2018·European Heart Journal·Franz-Josef NeumannUNKNOWN ESC Scientific Document Group
Dec 12, 2019·The New England Journal of Medicine·Julio A PanzaRobert O Bonow
Oct 14, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Suguru OhiraHitoshi Yaku
Jan 23, 2019·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Franz-Josef NeumannMichael O Zembala
Aug 23, 2019·The New England Journal of Medicine·Julio A PanzaRobert O Bonow
Dec 7, 2018·The Journal of Thoracic and Cardiovascular Surgery·Juan A Crestanello, Richard C Daly
Dec 12, 2019·The New England Journal of Medicine·Sanjiv SharmaJoel Lardizabal
May 12, 2021·Journal of Cardiovascular Translational Research·Jan NaarPetr Neužil

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.