Influence of body mass index on extent of coronary atherosclerosis and cardiac events in a cohort of patients at risk of coronary artery disease

Nutrition, Metabolism, and Cardiovascular Diseases : NMCD
R RossiMaria Grazia Modena

Abstract

To estimate if a meaningful relationship exists between body mass index (BMI) and the entity of coronary atherosclerosis, coronary events and mortality in a cohort of consecutive patients with suspected coronary artery disease (CAD). In this prospective study, we enrolled 1299 consecutive patients (905 [69.7%] males) who had undergone coronary angiography. Our sample consisted of 477 patients (36.8%) of normal weight; 567 (43.6%) overweight and 255 (19.6%) obese, according to the WHO classification. Conventional cardiovascular risk factors, BMI, endothelial function and subclinical inflammation were studied. Different angiographic CAD scores were used to quantify coronary atherosclerotic burden. In overweight and obese patients, respect to normal weight population, there is a higher prevalence of hypertension, hypercholesterolemia and diabetes mellitus, but BMI was not significantly associated with greater extent of coronary atherosclerosis. At follow-up (mean: 40; range: 24-82 months) obese and overweight patients showed a higher incidence of coronary events compared to the normal weight population (74.9% [obese] versus 62.7% [overweight] versus 53.2% [normal weight]; adjusted relative risk [obese versus overweight]: 1.08 [95%...Continue Reading

References

Feb 1, 1983·The American Journal of Cardiology·G G Gensini
Oct 8, 1999·The New England Journal of Medicine·E E CalleC W Heath
Jun 19, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·K TanakaA Takeshita
Dec 1, 2001·The American Journal of Cardiology·J Al SuwaidiA Lerman
Jan 15, 2002·Journal of the American College of Cardiology·Mary C CorrettiUNKNOWN International Brachial Artery Reactivity Task Force
Feb 19, 2002·Journal of the American College of Cardiology·Luis GrubergJoseph Lindsay
Apr 30, 2002·European Heart Journal·H-M LakkaJ T Salonen
Jul 18, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·S JonssonL Janzon
Aug 7, 2002·Circulation·Julian P J HalcoxArshed A Quyyumi
Oct 3, 2002·The American Journal of Cardiology·William B KannelRalph B D'Agostino
Nov 24, 2004·Archives of Internal Medicine·Michael E WidlanskyJ Michael Gaziano
Feb 3, 2005·International Journal of Cardiology·J AuerB Eber
Jun 29, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Angelo Avogaro, Saula Vigili de Kreutzenberg
Apr 26, 2006·The American Journal of Cardiology·Ronen RubinshteinBasil S Lewis
Aug 24, 2006·The New England Journal of Medicine·Kenneth F AdamsMichael F Leitzmann
May 29, 2007·The American Journal of Cardiology·Wael GalalDon Poldermans
Jun 30, 2007·The American Journal of Cardiology·Sabrina Deann Phillips, William Clifford Roberts
May 25, 2016·Journal of Diabetes and Its Complications·A S MeijnikmanL F Van Gaal

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Citations

Feb 25, 2014·Revista clínica española·A L Arrebola-MorenoJ C Kaski
Oct 24, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·G JoshyE Banks
Jan 21, 2014·Revista clínica española·A Sánchez-Recalde, J R González-Juanatey
Jan 21, 2014·Progress in Cardiovascular Diseases·Marjorie BastienJean-Pierre Després
Apr 3, 2012·European Journal of Clinical Investigation·Francesca CesariAlessandro Casini
Feb 11, 2015·The Canadian Journal of Cardiology·David Garcia-LabbéPaul Poirier
Aug 12, 2014·Current Opinion in Endocrinology, Diabetes, and Obesity·Katherine J StrisselBarbara S Nikolajczyk
Apr 30, 2017·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Mustafa YılmazHaldun Müderrisoğlu
Jun 27, 2019·Revista do Colégio Brasileiro de Cirurgiões·Daniel da Costa LinsÁlvaro Antônio Bandeira Ferraz
Aug 28, 2020·Current Problems in Cardiology·Natraj KattaMartin A Alpert

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