PMID: 2100825Jan 1, 1990Paper

Influence of calcium antagonists on renal function and secondary hyperparathyroidism in acute renal failure in rats

Renal Failure
D NeuserS Kazda

Abstract

Glycerol-induced acute renal failure (ARF) is characterized by an increase in serum creatinine, urea, and phosphate concentration, and severe impairment of creatinine clearance. Secondary hyperparathyroidism develops rapidly during ARF. The calcium antagonist nisoldipine clearly improves renal function, which becomes evident by an improvement of creatinine clearance and attenuation of the increase of serum creatinine, urea, and phosphate concentrations. Further secondary hyperparathyroidism is ameliorated by nisoldipine treatment. In spite of normalization of the hypocalcemia in ARF by nisoldipine, weak hyperparathyroidism persists, suggesting that hypocalcemia is not exclusively responsible for elevated parathyroid hormone serum levels in ARF.

References

Sep 1, 1978·Kidney International·P J Somerville, M Kaye
Jan 1, 1986·Annual Review of Medicine·S Klahr, E Slatopolsky
Aug 1, 1985·Experimental and Molecular Pathology·S M Lee, U F Michael
Oct 1, 1986·The Journal of Clinical Investigation·S Lopez-HilkerE Slatopolsky
Jun 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J SilverL M Sherwood
Dec 1, 1985·The Journal of Urology·L Hertle, B Garthoff
Mar 1, 1973·Annals of Internal Medicine·S G MassryC R Kleeman
Aug 1, 1973·Kidney International·C D Arnaud
Mar 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·I Clark, F Rivera-Cordero
Mar 1, 1971·The Journal of Clinical Investigation·E SlatopolskyN S Bricker
Mar 1, 1983·Proceedings of the Society for Experimental Biology and Medicine·D GoldfarbH E Eliahou
Oct 1, 1981·The Journal of Clinical Endocrinology and Metabolism·S MadsenJ Ladefoged
Jul 1, 1981·The American Journal of Medicine·L S IbelsR Weil

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Michael R Rickels, Susan J Mandel
Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Richard H StoneCathy A Brown
Annals of Emergency Medicine
G P ZalogaB Chernow
© 2021 Meta ULC. All rights reserved