Influence of cardiopulmonary vagal afferent activity on carotid chemoreceptor and baroreceptor reflexes in the dog.

Circulation Research
H KoikeP G Schmid

Abstract

The goal of this study was to determine if physiological levels of cardiopulmonary vagal afferent activity modulate carotid chemoreceptor and baroreceptor reflexes. In anesthetized, ventilated dogs, the aortic nerves and the cervical sympathetic trunks were cut, and atropine was administered so that vagotomy would interrupt only cardiopulmonary afferent impulses. Reflex vascular responses were observed in perfused gracilis muscle and hindpaw. Carotid chemoreceptors were activated with nicotine or hypoxic, hypercapnic blood; carotid baroreceptors were stimulated by changes in carotid pressure. Interruption of vaga afferents augmented reflex vascular responses during changes incarotid pressure from 75 to 125 mm Hg. Interruption of cardiopulmonary vagal afferents potentiated reflex vasoconstrictor (muscle), vasodilator (paw), and vasopressor responses to activation of the carotid chemoreceptors. The potentiation of the chemoreceptor reflex frequently occurred in the absence of increases in base-line vascular resistance. Vagotomy also potentiated ventilatory responses to stimulation of the carotid chemoreceptors in spontaneously breathing dogs. The results indicate that interruption of cardiopulmonary afferents potentiates the vasc...Continue Reading

References

Apr 1, 1975·The American Journal of Physiology·Y Uchida
Apr 11, 1975·Brain Research·A MallianiP J Schwartz
Apr 1, 1972·The Journal of Clinical Investigation·C B HigginsE Braunwald
May 1, 1973·The Journal of Clinical Investigation·A L MarkP G Schmid
Dec 1, 1971·Acta Physiologica Scandinavica·B Lisander, J Martner
Nov 1, 1970·Acta Physiologica Scandinavica·B Oberg, S White
Feb 1, 1971·Journal of Applied Physiology·A J Edis, J T Shepherd
Sep 1, 1969·The American Journal of Physiology·H R PillsburyE D Freis
Jun 29, 1953·The Journal of Physiology·A S PAINTAL
Apr 1, 1959·The American Journal of Physiology·D M AVIADO, C F SCHMIDT
Apr 1, 1963·The Journal of Physiology·J C COLERIDGE, C KIDD
Feb 1, 1963·The American Journal of Cardiology·L COSTANTIN

❮ Previous
Next ❯

Citations

Feb 14, 1979·Pflügers Archiv : European journal of physiology·S DelpierreC Grimaud
Apr 19, 2005·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Elizabeth A Martin, Nisha Charkoudian
Jul 1, 1987·Journal of the Autonomic Nervous System·M L SmithS A Nunneley
Dec 1, 1993·Journal of the American College of Cardiology·G PomidossiG Mancia
Feb 1, 2003·Autonomic Neuroscience : Basic & Clinical·Hiroshi SuzukaYoshiaki Hayashida
Jun 1, 1980·The Journal of Clinical Investigation·J L WalkerM D Thames
Oct 1, 1985·The Journal of Clinical Investigation·R G Victor, A L Mark
Dec 26, 2006·Autonomic Neuroscience : Basic & Clinical·J E de C LacerdaE M Krieger
Oct 18, 2011·Experimental Physiology·Paul J Fadel, Peter B Raven
Nov 12, 2015·BioMed Research International·Antonio CrisafulliShigehiko Ogoh
Mar 1, 1976·Progress in Cardiovascular Diseases·F M AbboudP G Schmid
Oct 22, 1979·The American Journal of Cardiology·F M Abboud
May 4, 2011·Autonomic Neuroscience : Basic & Clinical·Vanessa Moraes BezerraDeoclécio Alves Chianca
Nov 16, 2010·Neuroscience Letters·Vanessa Moraes BezerraDeoclécio Alves Chianca
Apr 3, 2012·Respiratory Physiology & Neurobiology·Peijun GuiMasahiro Kohzuki
Aug 4, 2016·Journal of Clinical Monitoring and Computing·Kavita YadavK K Deepak
Nov 26, 2008·Brain Research·Irina TopchiyDavid W Carley
Jul 14, 2010·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·T L FernandesE M Krieger
Mar 9, 2004·The Journal of Physiology·Masashi IchinoseTakeshi Nishiyasu
Feb 1, 1977·Archives internationales de physiologie et de biochimie·S DelpierreC Grimaud
Mar 5, 2011·Journal of Applied Physiology·Mikkel Lind-HolstFrank C Pott
Jul 17, 2020·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Remzi ArslanMehmet D Aydin
Jul 17, 1999·The American Journal of Physiology·N HoganB Casadei
Sep 27, 2018·Journal of Cardiovascular Development and Disease·Amélie CalmontPeter J Scambler

❮ Previous
Next ❯

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