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Influence of castration and testosterone replacement on hypothalamic tyrosine hydroxylase activity in the rat

Experientia

Aug 15, 1976

Craig W Beattie, Maureen A Martin

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Abstract

Hypothalamic tyrosine hydroxylase (TH) activity of castrate rats is modulated by testosterone propionate (TP) in vivo. Kinetic studies revealed that both Vmax and Km were virtually unaltered for substrate tyrosine in the presence of an excess of DMPH4 cofactor. TP replacement to castrat...read more

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Organum Vasculosum Laminae Terminalis
Metazoa
Pteridinones
Testolin
Castration
Tyrosine 3-Monooxygenase
Rats, Laboratory
Dystonia, DOPA-RESPONSIVE, With OR Without Hyperphenylalaninemia, Autosomal Recessive (Disorder)
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Influence of castration and testosterone replacement on hypothalamic tyrosine hydroxylase activity in the rat

Experientia

Aug 15, 1976

Craig W Beattie, Maureen A Martin

PMID: 8330

DOI: 10.1007/bf01933981

Abstract

Hypothalamic tyrosine hydroxylase (TH) activity of castrate rats is modulated by testosterone propionate (TP) in vivo. Kinetic studies revealed that both Vmax and Km were virtually unaltered for substrate tyrosine in the presence of an excess of DMPH4 cofactor. TP replacement to castrat...read more

Mentioned in this Paper

Organum Vasculosum Laminae Terminalis
Metazoa
Pteridinones
Testolin
Castration

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