PMID: 1768506Oct 1, 1991

Influence of centrifugal blood pumps on the elasticity of erythrocytes

ASAIO Transactions
H SchimaU Losert

Abstract

The influence of centrifugal blood pumps on the elasticity of erythrocytes was tested in an in vitro set-up. Fresh bovine blood was pumped by vaneless and impeller blood pumps with low and high hemolytic potential (1L priming volume, flow 5 L/min versus 150 mmHg, pumping time 6 hours). The elasticity of the red blood cells was measured by laser diffraction. Starting with an elasticity of 238 +/- 39, the overall change during 6 hours was 12 +/- 38 compared to a change of the control value of -13 +/- -58. Even a pump with very high hemolytic potential (Hemolysis index 21.9) did not cause relevant changes of elasticity. It is concluded that 1) elasticity is not a useful parameter to use in the evaluation of centrifugal pumps, and 2) the mechanical trauma caused by centrifugal pumps produces no relevant permanent alteration of the elastic properties of red blood cells, at least under in-vitro conditions.

Related Concepts

Bos indicus
Centrifugation
Elasticity
Medical Device Design
Erythrocyte Deformability
Erythrocytes
Heart-Assist Devices
Hemolysis

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