Influence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitus

Biological Trace Element Research
Jaroslav RacekVáClav Senft

Abstract

The aim of this study was to determine the effect of chromium (Cr)- enriched yeast on blood glucose and insulin variables, blood lipids, and blood markers of oxidative stress in persons with type 2 diabetes mellitus (median duration: 3.0 yr). Thirty-six subjects (9 men, 27 women; mean age: 61.3 yr; mean body mass index: 34.33 kg/m2) were supplemented with 400 microg Cr/d as Cr-enriched yeast (n = 19) or placebo (n = 17) for 12 wk in a randomized, double-blind study. The most interesting results were obtained by comparison of the change in the placebo group to the change in the Cr group. The Cr group showed a significantly greater increase in serum Cr compared to the placebo group (p < 0.05). Supplementation with Cr-enriched yeast was associated with a significant decrease in fasting serum glucose compared to placebo (p < 0.01). Blood markers of oxidative stress glutathione peroxidase activity and levels of reduced glutathione were essentially unchanged in the Cr group after 12 wk, but decreased significantly in the placebo group (p < 0.05, p < 0.01, respectively). Serum HbA1c and glycated protein (fructosamine) were essentially unchanged in the Cr group, whereas HbA1c tended to increase in the placebo group (from 6.94% to 7.11%...Continue Reading

Citations

Jan 17, 2013·Journal of Agricultural and Food Chemistry·Lu LiuHankie Uluko
Aug 28, 2013·Journal of Agricultural and Food Chemistry·Lu LiuJia-ping Lv
Feb 2, 2008·Chemical Research in Toxicology·Aviva Levina, Peter A Lay
Dec 17, 2008·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Hannah E Bartlett, Frank Eperjesi
Dec 3, 2013·Biological Trace Element Research·Christopher H Bailey
May 16, 2014·Canadian Journal of Diabetes·UNKNOWN Canadian Diabetes Association Clinical Practice Guidelines Expert CommitteeJeannette Goguen
May 17, 2011·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Shilpi SharmaVivek Agarwal
Jul 17, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ewelina Król, Zbigniew Krejpcio
Jun 2, 2012·Journal of Diabetes·Bhuvaneshwari SundaramRajat Sandhir
Mar 19, 2014·Journal of Clinical Pharmacy and Therapeutics·N SuksomboonA Yuwanakorn
Sep 24, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ewelina Król, Zbigniew Krejpcio
Jan 30, 2015·Journal of Inorganic Biochemistry·Mei Peng, Xiaoping Yang
Jun 5, 2016·Nutrition Reviews·Rebecca B CostelloRegan L Bailey
Jul 4, 2018·Journal of Food Science·Lu LiuJia-Ping Lv
Jul 6, 2017·Molecular Nutrition & Food Research·Haohai HuangHonglang Chen
Jan 12, 2019·Archives of Physiology and Biochemistry·Günter A Müller
Mar 20, 2010·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Olivia J PhungCraig I Coleman
Feb 16, 2017·Current Hypertension Reports·Sunil K PanchalLindsay Brown
Oct 9, 2015·The Journal of Nutrition·David J McIverAllison B Goldfine
Jul 23, 2019·Clinical and Experimental Pharmacology & Physiology·Fardin MoradiBahram Pourghassem Gargari
May 13, 2019·Biological Trace Element Research·Thiago F V BompadreHelder Louvandini
Jan 20, 2021·Clinical and Experimental Pharmacology & Physiology·Fateme KooshkiBahram Pourghassem Gargari
Nov 17, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Mohammad Javad TarrahiMarjan Mansourian
Apr 5, 2021·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Omid AsbaghiAmirmansour Alavi Naeini
May 21, 2021·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Mohammad Reza AminiSakineh Shab-Bidar
Jul 31, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Omid AsbaghiAlavi Naeini Amirmansour
Aug 12, 2021·Comprehensive Reviews in Food Science and Food Safety·Patricia R PereiraVania M F Paschoalin

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