Influence of CW microwave radiation on in vitro release of enzymes from retinol- treated hepatic lysosomes

Cell Biophysics
M J GalvinD I McRee

Abstract

Hepatic lysosomes were exposed in vitro to microwave radiation (2450 MHz) either prior to or simultaneously with treatment with retinol (vitamin A), and the release of the lysosomal enzymes, beta-glucuronidase, acid phosphatase, and cathepsin D, determined. A 60-min microwave exposure (10 or 100 mW/g) of retinol-treated lysosomes had no effect on the amount of release of beta-glucuronidase, cathepsin D, or acid phosphatase. In addition, 10 and 100 mW/g irradiation of lysosome fractions for 40 min prior to a 20-min retinol and microwave treatment, had no influence on the release of these enzymes. Finally, the effect of microwave radiation on the loss of latency of acid phosphatase and beta-glucuronidase from retinol-treated lysosomes was determined. Microwave radiation had no influence on the rate of appearance of these enzymes in the suspending medium. The results indicate that microwave radiation had no effect on the retinol-induced lysosomal enzyme release.

References

Feb 28, 1975·Annals of the New York Academy of Sciences·S SzmigielskiM Wiranowska
Jul 1, 1979·The Journal of Surgical Research·W J PetersK Iwano
Feb 23, 1979·Radiation and Environmental Biophysics·M A Stuchly
Feb 28, 1975·Annals of the New York Academy of Sciences·S SzmigielskiM Wiranowska
Nov 1, 1973·International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine·C P Mayers, J A Habeshaw
Feb 1, 1972·The American Journal of Physiology·W W FergusonA M Lefer
Nov 11, 1965·The New England Journal of Medicine·G Weissmann
Dec 1, 1967·Indian Journal of Pediatrics·R K Chandra
Jan 1, 1980·Radiation and Environmental Biophysics·M J GalvinD I McRee
Aug 1, 1962·Biochemical Pharmacology·C DE DUVEM WIBO
Mar 16, 1964·Biochimica Et Biophysica Acta·M ARTIZZUM U DIANZANI
Dec 26, 1964·Lancet·A C ALLISON, L MALLUCCI
Mar 20, 1937·The Journal of General Physiology·M L Anson
Jul 1, 1947·American Journal of Clinical Pathology·M A ANDERSCH, A J SZCZYPINSKI

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