Influence of D-lactate on metabolic acidosis and on prognosis in neonatal calves with diarrhoea

Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
Ingrid Lorenz

Abstract

Three hundred bucket-fed diarrhoeic calves up to the age of 21 days were used to investigate the degree in which D-lactic acid contributes to metabolic acidosis in bucket-fed calves with naturally acquired neonatal diarrhoea. Fifty-five percent of all diarrhoeic calves had serum D-lactate concentrations higher than 3 mmol/l. Mean (+/-SD) D-lactate values were 5.7 mmol/l (+/-5.3, median: 4.1 mmol/l). D-lactate values were distributed over the entire range of detected values from 0 to 17.8 mmol/l in calves with base excess of -10 to -25 mmol/l. Serum D-lactate concentration was higher in patients with ruminal acidosis (6.6 +/- 5.2 mmol/l; median: 5.9 mmol/l) than in those with physiological rumen pH (5.3 +/- 5.4 mmol/l; median: 3.7 mmol/l). There was no evidence of a correlation (r = 0.051) between the serum levels of D-lactate and creatinine (as an indicator of dehydration). D-lactate was correlated significantly with both base excess (r = -0.685) and anion gap (r = 0.647). The proportion of cured patients was not significantly different between the groups with elevated (>3 mmol/l) and normal serum D-lactate concentrations. This study shows that hyper-D-lactataemia occurs frequently in diarrhoeic calves, has no impact on prognos...Continue Reading

References

Nov 13, 1993·The Veterinary Record·D H Grove-White, D G White
Aug 2, 2001·The Journal of Nutrition·O O OmoleG A Zello

❮ Previous
Next ❯

Citations

May 11, 2011·Veterinary Clinical Pathology·Laura Y HardefeldtBenjamin J Darien
Feb 22, 2008·Journal of Veterinary Internal Medicine·A GentileW Klee
Apr 24, 2012·Journal of Veterinary Internal Medicine·R A PackerD P O'Brien
Sep 16, 2011·Irish Veterinary Journal·Ingrid LorenzSimon J More
Jul 2, 2014·The Veterinary Clinics of North America. Food Animal Practice·Ingrid Lorenz, Arcangelo Gentile
Jul 2, 2014·The Veterinary Clinics of North America. Food Animal Practice·Geof W Smith, Joachim Berchtold
Jan 29, 2009·The Veterinary Clinics of North America. Food Animal Practice·Peter D Constable
Jan 29, 2009·The Veterinary Clinics of North America. Food Animal Practice·Geof W Smith
Jan 29, 2009·The Veterinary Clinics of North America. Food Animal Practice·Joachim Berchtold
Oct 16, 2007·The Veterinary Journal·Ingrid Lorenz
Oct 9, 2007·The Veterinary Clinics of North America. Food Animal Practice·Linda M Vap, M Glade Weiser
Aug 6, 2011·Veterinary Surgery : VS·Sawsan Z YamoutJack R Snyder
Jul 22, 2014·The Journal of Small Animal Practice·I LangloisG A Zello
Oct 5, 2006·The Journal of Veterinary Medical Science·Yuko Shimomura, Hiroshi Sato
Nov 25, 2005·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Craig Petersen
Mar 20, 2018·Journal of the American Veterinary Medical Association·C Elizabeth BoudreauGeoffrey T Fosgate
Jun 27, 2018·Journal of Veterinary Internal Medicine·Florian M TrefzPeter D Constable
Oct 13, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·T BleyF Forterre
Jan 5, 2019·The Journal of Veterinary Medical Science·Tamako MiyazakiMasao Miyazaki
Jul 7, 2018·Frontiers in Veterinary Science·Francesca MarcatoKees van Reenen
Feb 10, 2009·The Veterinary Record·I Lorenz, A Lorch

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.