PMID: 6968722Apr 1, 1980Paper

Influence of daunorubicin on the survival of X-irradiated mammalian cells

International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine
D Dehove, F Laval

Abstract

Incubation with daunorubicin at concentrations having low toxicity decreases the survival of rat hepatoma (H4) cells irradiated in vitro with X-rays or gamma-rays. The radiosensitivity is modified whether the cells are incubated with the drug for 1 hour prior to or immediately after irradiation. The decrease in the DO is greater in the case of plateau cells than in the case of exponentially growing cells. The repair of sublethal damage is not influenced by the drug. However daunorubicin inhibits the repair of potentially lethal damage.

References

Jan 1, 1978·International Journal of Radiation Oncology, Biology, Physics·B W Fox
Feb 15, 1977·International Journal of Cancer. Journal International Du Cancer·J E ByfieldP Y Chan
Jan 1, 1977·International Journal of Radiation Oncology, Biology, Physics·W C DeweyE L Gillette
Jul 28, 1977·The New England Journal of Medicine·B A Chabner
Oct 24, 1959·Nature·M M ELKIND, H SUTTON

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Citations

Jan 22, 1992·Biochemical Pharmacology·A L EllisS Yanovich

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