PMID: 11912947Mar 27, 2002Paper

Influence of diabetes mellitus on the initial and long-term outcome of patients treated with coronary stenting

Journal of cardiology
Takashi TanigawaShin-ichi Momomura

Abstract

The long-term outcome of patients with diabetes who underwent stent placement has not been assessed comprehensively. Analysis of angioplasty procedures performed between January 1994 and December 1998 identified 140 diabetics (156 lesions) and 169 non-diabetics (187 lesions) who underwent successful stent placement. Follow-up was completed in 286 patients (93%) with a mean follow-up period of 2.8 +/- 1.3 years. Cardiac death, nonfatal myocardial infarction, coronary artery bypass grafting and repeat percutaneous transluminal coronary angioplasty were considered as adverse cardiac events. The primary clinical endpoint was event-free survival at 1 and 3 years. The primary angiographic endpoint was restenosis rate at follow-up angiography (follow-up rate 75% of 257 lesions). The diabetics were older (66 +/- 8 vs 62 +/- 11 years, p < 0.0005) with more risk factors such as hypertension (69% vs 57%, p < 0.05) and multivessel disease (69% vs 51%, p < 0.005). Final balloon size was smaller in diabetics than in non-diabetics (3.26 +/- 0.61 vs 3.39 +/- 0.53 mm, p < 0.05). Restenosis rate was significantly higher in diabetics than in non-diabetics (36% vs 24%, p < 0.05), but the target lesion revascularization in diabetics was not statist...Continue Reading

Citations

Nov 24, 2016·Scientific Reports·Daniel T C CoxKevin J Gaston
Feb 24, 2012·Biology Letters·Aurélie CoulonIrby J Lovette

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