Influence of dietary fatty acid composition and exercise on changes in fat oxidation from a high-fat diet

Journal of Applied Physiology
Jamie A CooperDale A Schoeller

Abstract

Acute high-fat (HF) diets can lead to short-term positive fat balances until the body increases fat oxidation to match intake. The purpose of this study was to examine the effects of a HF diet, rich in either mono-unsaturated or saturated fatty acids (FAs) and exercise, on the rate at which the body adapts to a HF diet.(13)C-labeled oleate and (2)H-labeled palmitate were also given to determine the contribution of exogenous vs. global fat oxidation. Eight healthy men (age of 18-45 yr; body mass index of 22 ± 3 kg/m(2)) were randomized in a 2 × 2 crossover design. The four treatments were a high saturated fat diet with exercise (SE) or sedentary (SS) conditions and a high monounsaturated fat diet with exercise (UE) or sedentary (US) conditions. Subjects stayed for 5 days in a metabolic chamber. All meals were provided. On day 1, 30% of energy intake was from fat, whereas days 2-5 had 50% of energy as fat. Subjects exercised on a stationary cycle at 45% of maximal oxygen uptake for 2 h each day. Respiratory gases and urinary nitrogen were collected to calculate fat oxidation. Change from day 1 to day 5 showed both exercise treatments increased fat oxidation (SE: 76 ± 30 g, P = 0.001; UE: 118 ± 31 g, P < 0.001), whereas neither se...Continue Reading

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Citations

Mar 3, 2012·European Journal of Applied Physiology·K R HawkinsJ A Cooper
Dec 24, 2013·European Journal of Nutrition·Sridevi Krishnan, Jamie A Cooper
Dec 3, 2014·Physiology & Behavior·Hui C ClevengerJamie A Cooper
Jan 28, 2012·Biochimica Et Biophysica Acta·Jennifer E Lambert, Elizabeth J Parks
Dec 15, 2015·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Marshall D McCue, Kenneth C Welch
Feb 18, 2014·Experimental Physiology·Hui C ClevengerJamie A Cooper
Oct 16, 2015·Journal of Sports Medicine·JohnEric W SmithMatthew J McAllister
Jun 16, 2012·Metabolism: Clinical and Experimental·Leah G GillinghamPeter J H Jones
Apr 17, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Sepideh KavianiJamie A Cooper
Mar 20, 2014·American Journal of Physiology. Endocrinology and Metabolism·Elizabeth A FrostSteven R Smith
Feb 5, 2013·Medicine and Science in Sports and Exercise·Takafumi AndoShigeho Tanaka
Oct 27, 2018·Molecular Medicine Reports·Xiang-Hua YuYa-Ling Tang
Nov 22, 2016·Current Opinion in Lipidology·Christophe Noll, André C Carpentier

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