Influence of Down's syndrome on management and outcome of patients with congenital intrinsic duodenal obstruction

Journal of Pediatric Surgery
Rangsan NiramisVaraporn Mahatharadol

Abstract

Children with Down's syndrome (DS) have been reported to have a high incidence of congenital heart disease (CHD) and respiratory tract infection. These anomalies and complications lead to poor outcomes, especially after treatment of congenital intrinsic duodenal obstruction (CIDO). The aim of this study was to review and compare the outcome of management of CIDO at a single tertiary institute for children in Thailand. We reviewed the medical records of patients with CIDO, who were treated at Queen Sirikit National Institute of Child Health (Bangkok, Thailand) from 1997 to 2006. The patients were classified into 2 groups: A = CIDO with DS and B = CIDO with non-DS (NDS). Each group was then divided into 2 subgroups: A(1) = DS without CHD, A(2) = DS with CHD, B(1) = NDS without CHD, and B(2) = NDS with CHD. Comparisons of management and outcome between group A and group B, subgroup A(1) and subgroup B(1), and subgroup A(2) and subgroup B(2) were performed. Statistical differences were analyzed by the chi(2) test at a P < .05. A total of 227 patients (male-female = 108:119) underwent surgical correction of CIDO. Of 227 patients, 86 (37.9%) were shown to have DS (group A), and 141 (62.1%) were NDS patients (group B). Demographic inf...Continue Reading

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Citations

Jan 18, 2012·British Journal of Anaesthesia·S M Walker
Aug 16, 2014·World Journal of Pediatrics : WJP·Qing-Jiang ChenQiang Shu
Sep 12, 2014·Journal of Nutrition and Metabolism·Sigrid BairdainBradley C Linden
Mar 17, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Benjamin H GootEduardo M da Cruz
Jul 29, 2016·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ji Ye KimJong-Hwa Kim

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