Influence of ethanol on the salsolinol excretion in healthy subjects

Alcohol
H HaberM F Melzig

Abstract

This report describes the change of salsolinol (SAL) levels in the urine of healthy subjects after ethanol ingestion. A new rapid method for SAL extraction from urine sample and a GC-MS assay were used to study the urinary SAL excretion in a group of adult males (n = 14) and females (n = 13) with and without ingestion of ethanol. The results of this study show that the urinary SAL output of all subjects is significantly influenced by the intake of ethanol. A decrease in the SAL level was found in the urine of most of the volunteers (n = 17), whereas only eight subjects showed an increase in the SAL level after administration of ethanol.

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Citations

Aug 13, 1998·Journal of Chromatography. B, Biomedical Sciences and Applications·F Musshoff, T Daldrup
Nov 27, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Frank Musshoff
Sep 12, 2013·Chemical Research in Toxicology·Mariko MurataShosuke Kawanishi
Feb 26, 1998·The New England Journal of Medicine·P G O'Connor, R S Schottenfeld
Jan 18, 2005·Alcoholism, Clinical and Experimental Research·Frank MusshoffBurkhard Madea
Jan 10, 2002·Alcoholism, Clinical and Experimental Research·C L EhlersL Carr
Apr 29, 1999·Clinical Chemistry and Laboratory Medicine : CCLM·L Chrostek, M Szmitkowski
Feb 1, 1996·Alcoholism, Clinical and Experimental Research·H HaberM F Melzig

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