Influence of exposure time on gene expression by human intestinal epithelial cells exposed to Lactobacillus acidophilus.

Applied and Environmental Microbiology
Sarah O'Flaherty, Todd R Klaenhammer

Abstract

Analysis of global temporal gene expression by human intestinal cells when exposed to Lactobacillus acidophilus revealed induction of immune-related pathways and NF-κB target genes after a 1-h exposure, compared to a 4- or 8-h exposure. Additionally, an L. acidophilus derivative expressing covalently bound flagellin resulted in increased induction of il8, cxc1, and cxcl2 compared to the parent L. acidophilus.

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Citations

May 29, 2013·The British Journal of Nutrition·Jonathan A LaneRita M Hickey
Apr 22, 2014·Antonie van Leeuwenhoek·Brant R Johnson, Todd R Klaenhammer
Nov 19, 2013·Applied and Environmental Microbiology·Francesca TurroniMarco Ventura
May 23, 2012·Journal of Dairy Science·M C EscobarM J Miller
Dec 7, 2018·Disease Models & Mechanisms·Matthew T PereiraLaura Palanker Musselman
Oct 14, 2020·Clinical and Translational Science·Mayur SarangdharBruce R Yacyshyn

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