PMID: 1189366Jan 1, 1975Paper

[Influence of fast electrons on the nucleic acid level and the biosynthsis of RNA in cells of the ascites tumor NK/Ly and the spleen of tumor-bearing mice].

Voprosy onkologii
Iu P ZerovI F Seĭts

Abstract

The results of investigations on total nucleic acids content and RNA turnover in the cells of tumor NK/Ly and of the spleen in tumor-bearing mice after single exposure to fast electrons are described. In every case the irradiation results in reliable changes of parameters under study. The pattern of changes in nucleic acids content and turnover in the spleen after the exposure to fast electrons is in a good agreement with the available data concerning the influence of x- and y-radiation. The irradiation action on nucleic acids content and turnover in ascites tumor NK/Ly cells is qualitatively and quantitatively similar to that in splenic cells.

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