PMID: 6990177May 1, 1980Paper

Influence of fat-rich versus carbohydrate-rich diets on bile acid kinetics, biliary lipids, and net steroid balance in hyperlipidemic subjects

Metabolism: Clinical and Experimental
E Andersén, K Hellström

Abstract

Altogether, 14 patients with hyperlipoproteinemia type IIA (n = 3), IIb (n = 4), or IV (n = 7) were maintained on diets in which 60% of the energy was supplied as fat or carbohydrates. The switch from the fat-rich to the carbohydrate-rich diet resulted in elevation of the plasma triglyceride levels. Although not consistent in all instances, the change of diet also resulted in an enhanced formation of both cholic acid and chenodeoxycholic acid and a higher contribution of deoxycholic acid in duodenal bile. Due to a reciprocal decrease in the excretion of neutral steroids in feces, the mean steroid balance remained unchanged. In all but four patients this switch of diets was associated with a decreased molar cholesterol concentration in duodenal bile obtained in the postabsorptive state.

References

Jan 1, 1979·Scandinavian Journal of Gastroenterology·E Andersén
Jun 1, 1972·European Journal of Clinical Investigation·E A Nikkilä, M Kekki
Nov 1, 1965·The Journal of Clinical Investigation·G M ReavenJ W Farquhar
Sep 17, 1957·Acta Physiologica Scandinavica·S LINDSTEDT

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Citations

Apr 10, 2017·Molecular Aspects of Medicine·Vance L AlbaughCharles R Flynn
Feb 1, 1985·The Proceedings of the Nutrition Society·T S Low-Beer
Mar 1, 1994·Zeitschrift für Ernährungswissenschaft·E A Trautwein
Jun 15, 1983·Klinische Wochenschrift·O Leiss, K von Bergmann
Mar 31, 2004·The American Journal of Clinical Nutrition·Peter H BisschopJohannes A Romijn

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