Influence of gender on selenoprotein W, glutathione peroxidase and selenium in tissues of rats

Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
J Y YehP D Whanger

Abstract

After feeding a commercial rodent chow for 8 weeks, tissues from male and female rats were collected and examined for selenium content, glutathione peroxidase (GPX) activities and selenoprotein W (Se-W) levels. There were no differences (P > 0.05) between plasma selenium content, plasma GPX activity, whole blood selenium content, or whole blood GPX activity between male and female rats. There was also no gender effect on selenium concentration in muscle, brain, spleen, and skin, but selenium concentration in liver was higher (P < 0.05) in female than in male rats. Western blots indicated that the tissue distribution of Se-W was similar in male and female rats. Se-W protein level was high in testes of male rats but very low in ovaries of female rats. Muscle and skin from female rats had significantly higher (P < 0.05) Se-W levels than from male rats. Consistent with Se-W content, the Se-W mRNA levels from female skins were significantly higher (P < 0.05) than from male rats. The expression of Se-W was different in various tissues and gender influenced this regulation in some tissues.

References

Sep 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·H TowbinJ Gordon
Apr 1, 1991·Clinics in Dermatology·J D Jester
Sep 12, 1995·Proceedings of the National Academy of Sciences of the United States of America·S C VendelandP D Whanger
May 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J R Prohaska, R A Sunde
Feb 1, 1996·Journal of Inorganic Biochemistry·M A BeilsteinP D Whanger

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Citations

Apr 27, 2011·Biological Trace Element Research·Dong YuShiwen Xu
Aug 13, 2011·Biological Trace Element Research·Hongfeng RuanShiwen Xu
Mar 10, 2009·Radiation Research·Fritz SieberJohn E Moulder
Feb 12, 2014·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Dong YuShi-Wen Xu
Dec 21, 2010·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Jin-Long LiZhao-Xin Tang
Feb 14, 2012·Molecular and Cellular Endocrinology·Maxime Y TondreauJean-François Bilodeau
Oct 30, 2014·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Dong YuShi-Wen Xu
Mar 4, 2005·Critical Reviews in Toxicology·Michelle L O'BrienHoward P Glauert
Sep 22, 2005·Endocrine Reviews·J KöhrleJ E Dumont
Feb 15, 2002·Nutritional Neuroscience·P D Whanger
Jan 4, 2019·Journal of Molecular Neuroscience : MN·Joanna A RuszkiewiczMichael Aschner
Jun 29, 2011·Journal of Inorganic Biochemistry·Rihua WangShiwen Xu

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