Influence of glucagon on systolic time intervals during induction of anaesthesia with barbiturate.

Acta Anaesthesiologica Scandinavica
M Ibler, M Dalsgaard

Abstract

The systolic time intervals and calculated parameters of PEP/LVET (pre-injection period/left ventricular ejection time-ratio) and 1/PEP2 before and after induction of anaesthesia with the barbiturate enibomal (Narcodorm) were studied noninvasively in eight surgical patients after pre-treatment with a bolus dose of glucagon. The mean difference between the PEP/LVET-ratio before and after induction was 0.06, and the mean difference between 1/PEP2 before and after induction was -8. The corresponding values in the control group consisting of 12 patients were 0.09 and -28, respectively, suggesting a somewhat greater depression of cardiac function in this group. However, no statistically significant difference at the 5% level was found between changes in the glucagon group and controls. The influence of barbiturates and glucagon on cardiac function is discussed.

References

Jan 1, 1975·Acta Anaesthesiologica Scandinavica·M Ibler, M Dalsgaard
Nov 1, 1971·Proceedings of the Society for Experimental Biology and Medicine·T D Giles, G E Burch
Apr 1, 1969·The American Journal of Cardiology·A M WeisslerC D Schoenfeld
Sep 1, 1964·Anesthesiology·T H LIB E ETSTEN

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