Influence of harvest stage on the pharmacological effect of Angelica dahurica

Botanical Studies
Wei-Hong LiangYuh-Chyang Charng

Abstract

Baizhi (Angelica dahurica) has been widely used as a traditional Chinese herbal medicine, functional food and cosmetic product ingredient, mostly because of the high furanocoumarin compounds in roots. The cropping system of Baizhi with its unique summer dormancy feature, is easily affected by the transition of its growth stages. The aim of this study was to analyze the quantity (size, form and dry weight [DW]) and quality (antioxidant and furanocoumarin content) of taproot and lateral root from three growth stages of Baizhi; vegetative (V-stage), summer dormancy (S-stage) and bolting stage (B-stage). Root length and diameter were lower at V-stage than the other two stages, and S-stage had higher lateral root to total root ratio. However, the highest root DW was observed at S-stage. Antioxidant activity was revealed by 2,2-diphenyl-L-picrylhydrazyl and Fe2+ chelating assay, and the content of six furanocoumarin compounds, including xanthotoxin, bergapten, oxypeucedanin, imperatorin, phellopterin and isoimperatorin, was analyzed by liquid chromatography. Although the antioxidant activity was less at S-stage than the other stages, furanocoumarin contents showed little variation. Considering the high DW and stable furanocoumarin co...Continue Reading

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May 28, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Izabela Szymborska-SandhuZenon Węglarz
Jun 12, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Renato BruniFederica Pellati
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Aug 29, 2021·Plants·Javad Mottaghipisheh

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