Abstract
Reflux esophagitis is caused by esophageal motor dysfunction in patients with sufficient gastric acid secretion. Helicobacter pylori causes atrophic gastritis and influences gastric acid secretion. Hiatus hernia (HH) of the esophagus causes motor dysfunction in the lower esophagus. Therefore, this study aimed to test whether H. pylori infection, gastric mucosal atrophy and HH are predictive factors for reflux esophagitis. Helicobacter pylori infection was examined in 781 patients by the measurement of serum immunoglobulin (Ig)G antibody, bacteriological culture and histological examination of biopsy specimens. The prevalence of HH, endoscopically identified gastric mucosal atrophy (closed- or open-type) and reflux esophagitis were investigated by reviewing endoscopic films. Investigated patients were divided into three age groups, under 49, 50-69, and over 70 years. The prevalence of esophagitis, H. pylori infection, gastric mucosal atrophy, and HH were compared to identify the possible predictive factors for reflux esophagitis by using logistic regression analysis. Sixty-nine patients with reflux esophagitis were found among the 781 investigated cases. The odds ratios of negative H. pylori infection, endoscopically identified ...Continue Reading
References
Apr 1, 1979·Digestive Diseases and Sciences·R A Wright, A L Hurwitz
Apr 1, 1992·Journal of Clinical Pathology·P SipponenK Seppälä
Mar 1, 1991·Gastroenterology·S Sloan, P J Kahrilas
Apr 1, 1990·Gastroenterology·T A Miller
Apr 1, 1987·Gastroenterologia Japonica·K MikiK Takahashi
Aug 1, 1995·Gastroenterology·R K MittalJ Dent
Nov 1, 1994·Gut·Y YasunagaY Matsuzawa
Aug 1, 1993·Gut·E el-OmarK E McColl
Jan 1, 1993·Scandinavian Journal of Gastroenterology. Supplement·R H Hunt
Dec 1, 1995·Digestive Diseases and Sciences·P KasapidisE Xynos
Jul 1, 1996·Gastroenterology·D ArmstrongL Wallin
May 1, 1996·Gut·A W HarrisJ H Baron
Oct 1, 1996·Gastroenterology·E GaudioD Alvaro
Nov 1, 1996·Gastroenterology·M F Vaezi, J E Richter
Dec 1, 1996·Gastroenterology·Z LiM F Goy
Jan 1, 1997·Digestive Diseases and Sciences·B F Werdmuller, R J Loffeld
Jan 1, 1997·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·A CsendesP Csendes
Dec 10, 1997·Gut·Y KinoshitaT Chiba
May 12, 1998·The American Journal of Physiology·L A Scheving, W Gardner
Jul 3, 1998·Gastroenterology·J J VicariJ E Richter
Sep 10, 1998·Helicobacter·R V VaranasiK T Wilson
Oct 30, 1998·Journal of Gastroenterology and Hepatology·T MaekawaT Chiba
Feb 19, 1999·Journal of Clinical Pathology·M C GunnK P West
Jun 3, 1999·Helicobacter·M MiharaG Kajiyama
Oct 27, 1999·Journal of Gastroenterology·T ShirotaT Sekiguchi
Apr 12, 2000·Alimentary Pharmacology & Therapeutics·J C WuS C Chung
Jun 10, 2000·Alimentary Pharmacology & Therapeutics·H HamadaM Kawanishi
Oct 12, 2000·Digestion·R J LoffeldE J Kuipers
Nov 15, 2000·Gut·O Lundgren
Feb 24, 2001·Journal of Gastroenterology and Hepatology·K AmanoY Kinoshita
Aug 1, 1963·Journal of Cellular Physiology·H SANUI, N PACE
Citations
Aug 26, 2006·Journal of Gastroenterology·Yoshikazu Kinoshita, Kyoichi Adachi
Apr 28, 2005·Journal of Gastroenterology and Hepatology·Takafumi MiharaYoshikazu Kinoshita
Aug 25, 2006·Journal of Gastroenterology and Hepatology·Kenji FurutaYoshikazu Kinoshita
Nov 23, 2007·Journal of Gastroenterology and Hepatology·Katsuhiko IwakiriChoitsu Sakamoto
Jul 14, 2010·Journal of Gastroenterology and Hepatology·Takashi KawaiTatsuya Aoki
Jan 14, 2011·Journal of Gastroenterology and Hepatology·Khean-Lee Goh
Nov 1, 2008·Therapeutic Advances in Gastroenterology·Yoshikazu Kinoshita, Shunji Ishihara
Apr 19, 2008·Internal Medicine·Takane AzumiYoshikazu Kinoshita
Apr 15, 2009·Journal of Gastroenterology·Yasuhiro Fujiwara, Tetsuo Arakawa
Jun 16, 2009·Journal of Gastroenterology·Yoshikazu KinoshitaYuji Amano
Mar 19, 2013·Journal of the Chinese Medical Association : JCMA·Yasushi FunakiKunio Kasugai
Apr 17, 2015·Internal Medicine·Kyoichi AdachiYoshikazu Kinoshita
Mar 7, 2015·Internal Medicine·Kozue HanadaYoshikazu Kinoshita
Dec 23, 2006·Gastrointestinal Endoscopy·Ken-ichi GodaMitsuru Kaise
Aug 10, 2004·Alimentary Pharmacology & Therapeutics·K YamamoriT Arakawa
May 3, 2013·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Kingo HirasawaShin Maeda
Jun 1, 2012·Current Therapeutic Research, Clinical and Experimental·Shino ShimuraYoshikazu Kinoshita
Mar 22, 2012·The American Journal of Gastroenterology·Yoshikazu KinoshitaUNKNOWN Japan TWICE Study Group
Sep 21, 2007·Journal of Clinical Gastroenterology·Tseng-Shing Chen, Full-Young Chang
May 22, 2019·Journal of Gastroenterology and Hepatology·Kyoichi AdachiYoshikazu Kinoshita
Oct 8, 2005·Scandinavian Journal of Gastroenterology·Ikuyo MishimaYoshikazu Kinoshita