Influence of leptomeningeal collateral pattern on the prognostic value of mismatch in acute anterior circulation stroke

Journal of Computer Assisted Tomography
Alexander SpiessbergerSpyros Kollias

Abstract

This study aimed to investigate whether and to what degree leptomeningeal collateral flow as detected on angiography influences the prognostic value of computed tomography perfusion-estimated mismatch in interventional treatment of acute anterior circulation stroke. Thirty-eight consecutive patients with acute anterior circulation stroke who received interventional neuroradiologic treatment were assigned one of 2 groups depending on the patient's degree of collateral flow (18 patients with poor collaterals, 20 patients with high degree collaterals) according to the American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology grading system. In a multiregression model, we investigated a possible interaction between 2 independent variables mismatch ratio and degree of collateral flow using a "centered" variable approach. The mismatch ratio per se showed a significant correlation with final clinical outcome (β coefficient, -0.79; P = 0.02); whereas, there was no interaction shown between mismatch degree of collateral flow (β coefficient, 0.54; P = 0.1). This study suggests that the predictive value of computed tomography perfusion-estimated mismatch is not influenced by the degree of leptom...Continue Reading

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Citations

May 26, 2016·Arquivos de neuro-psiquiatria·Heitor Castelo Branco Rodrigues AlvesAntonio J Rocha
Aug 8, 2018·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Maher SaqqurAshfaq Shuaib

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