Influence of liposphere preparation on butyl-methoxydibenzoylmethane photostability

European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V
Valentina IannuccelliS Scalia

Abstract

The incorporation of butyl-methoxydibenzoylmethane (BMDBM), one of the most efficient and frequently used UV-A blockers, into lipospheres was examined in order to decrease the light-induced sunscreen degradation. Lipospheres, obtained by the melt technique and using tristearin as the lipid material and hydrogenated phosphatidylcholine as the emulsifier, showed proper features in terms of size (10-40 microm), BMDBM loading level (21.63% +/- 0.90%, w/w) and physical state. Photolysis studies, involving irradiation of lipospheres with simulated sunlight before and after their introduction in emulsion formulations, demonstrated a relevant enhancement of the encapsulated sunscreen photostability in comparison with unencapsulated BMDBM.

References

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Citations

Oct 16, 2007·Skin Pharmacology and Physiology·V IannuccelliS Scalia
Feb 28, 2007·BMC Dermatology·Helena GonzalezAnn-Marie Wennberg
Jul 31, 2009·AAPS PharmSciTech·Pankaj Pathak, Mangal Nagarsenker
Dec 24, 2013·Colloids and Surfaces. B, Biointerfaces·C C LiY W Chen-Yang
Apr 2, 2014·TheScientificWorldJournal·Amber VyasBina Gidwani
Jul 30, 2011·AAPS PharmSciTech·Christianne Mounir Zaki RizkallaIman Ibrahim Soliman
Mar 24, 2011·Journal of Microencapsulation·Randa LatifShereen Tawakkol
Sep 12, 2008·Drug Development and Industrial Pharmacy·Santo Scalia, Matteo Mezzena
Nov 11, 2014·Drug Development and Industrial Pharmacy·Hamed HamishehkarMaryam Kouhsoltani
Nov 14, 2014·Expert Opinion on Drug Delivery·Santo ScaliaDaniela Traini
Apr 5, 2007·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Rosanna TursilliSanto Scalia
Jun 6, 2012·Pharmaceutical Development and Technology·Christianne Mounir Zaki RizkallaIman Ibrahim Soliman
Jan 1, 2014·International Journal of Pharmaceutics·Eleonora MarettiValentina Iannuccelli
Apr 1, 2008·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·R P RaffinS S Guterres
Sep 24, 2020·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Rhys B MurphyTamim A Darwish
Dec 7, 2007·The Journal of Pharmacy and Pharmacology·Santo ScaliaValentina Iannuccelli
Aug 5, 2010·Journal of Microencapsulation·Y A GomaaL K El-Khordagui

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