Influence of metabolic indicators, smoking, alcohol and socioeconomic position on mortality after breast cancer

Acta Oncologica
Signe Benzon LarsenSusanne Oksbjerg Dalton

Abstract

Factors differently distributed among social groups like obesity, metabolic syndrome, diabetes, smoking, and alcohol intake predict survival after breast cancer diagnosis and therefore might mediate part of the observed social inequality in survival. We conducted a cohort study among 1250 postmenopausal breast cancer patients identified among 29 875 women in the Danish Diet, Cancer and Health Study. Participants completed questionnaires and anthropometric measurements were made at enrollment. Information on survival, socioeconomic position, and comorbidity was obtained by linkage to national Danish registries. Clinical information was obtained from the nationwide Danish Breast Cancer Database. Selected information was obtained from hospital records at time of diagnosis. All analyses were based on Cox proportional hazard models, using death from all causes as outcome. Median follow-up was 9.6 years [interquartile range (IQR), 2.2-17.0 years]. The hazard ratio (HR) for death from all causes increased with lower education (p for trend, 0.01). Adjustment for disease-related prognostic factors, comorbidity and metabolic indicators measured as BMI, waist circumference and diabetes, and smoking and alcohol affected but did not explain...Continue Reading

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Citations

Dec 3, 2016·Acta Oncologica·Signe Benzon LarsenSusanne Oksbjerg Dalton
Jun 22, 2017·Oncology Nursing Forum·Kimberly RodriguezRobin Skrine
Apr 11, 2018·Breast Cancer Research and Treatment·Signe Benzon LarsenPernille Envold Bidstrup
Oct 31, 2019·Scandinavian Journal of Urology·Caroline Sophie Lerhmann-LercheSusanne Oksbjerg Dalton
May 26, 2020·Perspectives in Public Health·S Lago-PeñasF Reyes
Jun 5, 2020·Breast Cancer Research and Treatment·Cassia Bree TrewinGiske Ursin
Apr 25, 2015·Acta Oncologica·Christoffer Johansen, Susanne Oksbjerg Dalton
Oct 28, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Pete T KinnunenTeemu J Murtola
May 1, 2021·Cancer Control : Journal of the Moffitt Cancer Center·Nina AfsharRoger L Milne

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