PMID: 16629143Apr 25, 2006Paper

Influence of metal exposure history on the bioaccumulation and subcellular distribution of aqueous cadmium in the insect Hydropsyche californica

Environmental Toxicology and Chemistry
D J CainSamuel N Luoma

Abstract

The influence of metal exposure history on rates of aqueous Cd accumulation, elimination, and subcellular distribution was examined in the aquatic insect Hydropsyche californica. Specimens were obtained from a reference site and a metal-contaminated site and returned to the laboratory where they were continuously exposed to aqueous Cd (518 ng/L, nominal) for 6 d, followed by 9 d of depuration. Rates of Cd accumulation and elimination were similar in insects from the two sites. Efflux rate constants, k((e), ranged from 0.20 to 0.24/d (t 1/2 approximately 3 d). Immediately following exposure, the cytosol accounted for 40% of the body burden in insects from both sites; however, 89 +/- 2% of the cytosolic Cd was associated with metallothionein-like proteins (MTLP) in insects from the contaminated site, compared to 60 +/- 0% in insects from the reference site. The concentration of Cd bound to non-MTLPs (representing potentially Cd-sensitive proteins) was significantly greater in the insects from the reference site (134 +/- 7 ng/g) than in those from the contaminated site (42 +/- 2 ng/g). At the end of the depuration period, 90% of the accumulated Cd body burden had been eliminated, and Cd concentrations in MTLPs and non-MTLPs were s...Continue Reading

Citations

Jun 19, 2008·Proceedings of the National Academy of Sciences of the United States of America·David B BuchwalterTheodore Garland
Dec 20, 2013·Environmental Science and Pollution Research International·Alina KafelPaweł Migula
May 27, 2008·Ecotoxicology and Environmental Safety·Lian-Zhen LiXiao-San Luo
Oct 29, 2010·Integrated Environmental Assessment and Management·Mascha N RubachStephen J Maund
Dec 25, 2010·Integrated Environmental Assessment and Management·William J AdamsChris M Wood
May 20, 2015·Environmental Science and Pollution Research International·Mariusz TszydelMateusz Zieliński
Jun 8, 2014·Ecotoxicology and Environmental Safety·Xiaotian LvBaoyuan Guo
Apr 13, 2012·The Journal of Experimental Biology·Monica D PoteatDavid B Buchwalter
Feb 28, 2009·Environmental Science & Technology·Lingtian XieDavid B Buchwalter
Jul 19, 2011·Aquatic Toxicology·Lingtian Xie, David B Buchwalter

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