Influence of multidrug resistant organisms on the outcome of diabetic foot infection

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Nese SaltogluTurkish Society of Clinical Microbiology and Infectious Diseases, Diabetic Foot Infections Study Group

Abstract

We described the clinical outcomes of the diabetic patients who had foot infections with multidrug resistant organisms. We included the patients with diabetic foot infections (DFI) from 19 centers, between May 2011 and December 2015. Infection was defined according to IDSA DFI guidelines. Patients with severe infection, complicated moderate infection were hospitalized. The patients were followed-up for 6 months after discharge. In total, 791 patients with DFI were included, 531(67%) were male, median age was 62 (19-90). Severe infection was diagnosed in 85 (11%) patients. Osteomyelitis was diagnosed in 291(36.8%) patients. 536 microorganisms were isolated, the most common microorganisms were S. aureus (20%), P. aeruginosa (19%) and E. coli (12%). Methicillin resistance (MR) rate among Staphylococcus aureus isolates was 31%. Multidrug resistant bacteria were detected in 21% of P. aeruginosa isolates. ESBL (+) Gram negative bacteria (GNB) was detected in 38% of E. coli and Klebsiella isolates. Sixty three patients (8%) were re-hospitalized. Of the 791 patiens, 127 (16%) had major amputation, and 24 (3%) patients died. In multivariate analysis, significant predictors for fatality were; dialysis (OR: 8.3, CI: 1.82-38.15, p=0.006), ...Continue Reading

Citations

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Apr 8, 2021·African Journal of Laboratory Medicine·Adeyemi T AdeyemoAaron O Aboderin
Apr 16, 2021·The International Journal of Lower Extremity Wounds·Nese SaltogluUNKNOWN KLİMİK Society, Diabetic Foot Study Group
Apr 29, 2021·The International Journal of Lower Extremity Wounds·Javier Aragón-SánchezChristian Murillo-Vargas
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Oct 16, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Michal LeibovitchKaren Olshtain-Pops

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