PMID: 7082418Mar 1, 1982Paper

Influence of native and randomized peanut oil on lipid metabolism and aortic sudanophilia in the vervet monkey

D KritchevskyJ P du Plessis


Vervet monkeys (Cercopithecus aethiops pygerethrus) were fed cholesterol-free, semipurified diets containing 40% sucrose, 25% casein, 15% cellulose and 14% peanut oil (PNO), randomized peanut oil (RPNO) or corn oil (CO). After 4 months, serum cholesterol and triglyceride levels, serum lecithin-cholesterol acyl transferase (LCAT) activity and plasma lipoprotein lipase (LPL) activity were similar in all groups. Livers of monkeys fed CO converted 156% more acetate and 24% more mevalonate to cholesterol than those of monkeys fed RPNO. Cholesterogenesis in RPNO-fed monkeys was enhanced compared to PNO (68% from acetate; 62% from mevalonate). Incidence of atherosclerosis was 33% in monkeys fed RPNO, 80% in those fed CO and 90% in those fed PNO. Extent of sudanophilia was lowest in aortas of monkeys fed RPNO. Incidence of arteriosclerosis was 40% in monkeys fed CO, 56% in those fed RPNO and 70% in those fed PNO. Extent of aortic surface showing arteriosclerosis was highest in monkeys fed RPNO.


Sep 1, 1974·Atherosclerosis·D VesselinovitchR W Wissler
Feb 1, 1973·Biochemical Medicine·A G LackoL A Soloff
Mar 1, 1973·Atherosclerosis·D KritchevskyR W Wissler
Jul 1, 1971·Atherosclerosis·D KritchevskyR W Wissler
Apr 1, 1958·Proceedings of the Society for Experimental Biology and Medicine·J AVIGAN, D STEINBERG
Jun 1, 1949·The Journal of Experimental Medicine·G L DUFF, G C McMILLAN


Sep 1, 1987·Lipids·D M Klurfeld, D Kritchevsky
Nov 1, 1983·Lipids·H K Kim, D Kritchevsky
Sep 4, 1998·Lipids·D KritchevskyD M Klurfeld
Apr 30, 1995·Clinica Chimica Acta; International Journal of Clinical Chemistry·R M FisherK N Frayn
Dec 1, 1988·International Journal of Bio-medical Computing·H PincéJ L Willems
Dec 1, 1995·International Journal of Cardiology·E I NikolaevaA A Nikolaeva
Jan 1, 1988·Trends in Genetics : TIG·G Bulfield
Jan 31, 1991·The New England Journal of Medicine
Apr 1, 1995·The Journal of Pharmacy and Pharmacology·M NoaJ Magraner
Nov 1, 1987·Atherosclerosis·D KritchevskyG T Goodman
Sep 1, 1986·Arteriosclerosis : an Official Journal of the American Heart Association, Inc·L M AldersonR J Nicolosi
Aug 1, 2008·Journal of the American Mosquito Control Association·Devi S SumanShri Prakash
Sep 29, 2018·Food Science and Biotechnology·Wai-Ming KokSit-Foon Cheng

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