PMID: 9438643Jan 23, 1998Paper

Influence of nutrition on urinary oxalate and calcium in preterm and term infants

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
B HoppeE Leumann

Abstract

Few data for normal urinary oxalate (Ox) and calcium (Ca) excretion related both to gestational age and nutritional factors have been reported in preterm or term infants. We therefore determined the molar Ox and Ca to creatinine (Cr) ratios in spot urines from 64 preterm and 37 term infants aged 1-60 days, either fed formula or human milk (HM). Only vitamin D was supplemented; renal or metabolic diseases were excluded. Urinary Ox/Cr ratio was higher in preterm than in term infants, both when formula fed (1st month 253 vs. 180 mmol/mol and 2nd month 306 vs. 212 mmol/mol; P<0.05) or HM fed (206 vs. 169 mmol/ mol and 283* vs. 232 mmol/mol; *P<0.05). Ox/Cr was also higher in formula- than HM-fed preterm infants. The ratio increased during the first 2 months of life irrespective of nutrition. Urinary Ca/Cr ratio was comparable in all groups during the 1st month of life, except for a lower (P < 0.05) value in term infants fed HM (0.10 mol/mol). It increased in all groups during the 2nd month of life, being highest in HM-fed preterm infants (1.86 mol/mol). In conclusion, urinary Ox and Ca excretion is influenced by both gestational age and nutrient intake in preterm and term infants.

Citations

Sep 7, 2004·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Narendra AladangadyT James Beattie
Dec 11, 2008·Journal of Inherited Metabolic Disease·S IllsingerA M Das
Oct 24, 2000·Kidney International·E A Schell-FeithB J van der Heijden
Oct 23, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·A NarendraJ Beattie
Oct 23, 2004·Nephron. Clinical Practice·William G van't Hoff
Aug 27, 2014·Clinics in Perinatology·Stephanie M Jernigan
Sep 18, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Eveline A Schell-FeithAlbert J van der Heijden
Apr 2, 2004·American Journal of Medical Genetics. Part a·Mario GiuffrèGiovanni Corsello
May 17, 2003·European Journal of Pediatrics·Vasilios I GiaprosStyliani K Andronikou
Aug 7, 2018·EFSA Journal·UNKNOWN EFSA Panel on Dietetic Products, Nutrition and Allergies (EFSA NDA Panel)Monika Neuhäuser-Berthold

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