PMID: 9434304Jan 22, 1998Paper

Influence of OSEM, elliptical orbits and background activity on SPECT 3D resolution recovery

Physics in Medicine and Biology
T S PanM A King

Abstract

In maximum-likelihood expectation-maximization (MLEM) reconstruction of SPECT images, if both attenuation correction (AC) and detector response correction (DRC) are included, the reconstruction can be too time consuming to be clinically useful. With use of the ordered-subset expectation-maximization (OSEM) reconstruction, it has been reported that the reconstruction time can be substantially reduced. We investigated the reconstruction of point sources in a non-uniform attenuation medium in terms of the normalized FWHM of these sources. We compared MLEM versus OSEM reconstructions; circular versus elliptical orbits; and the presence versus the absence of background activity in the object. We found: (i) that OSEM does speed up the reconstruction by a factor of 10 over MLEM; (ii) that the resolution recovery does not depend on the type of orbit if both AC and DRC are included in the reconstruction; however, when there is background activity, a significant number of iterations are required to alleviate the effect of orbit; (iii) that background activity significantly slows down the resolution recovery of the point sources; and (iv) that if reconstruction only includes AC, and not DRC, changing orbit can change isotropy of recovered...Continue Reading

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Citations

Oct 23, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Arda KönikMichael A King
Jul 21, 1998·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·H Iida, S Eberl
Apr 11, 2008·Physics in Medicine and Biology·Andrew B HwangBruce H Hasegawa
Feb 25, 2009·Medical Physics·P Hendrik Pretorius, Michael A King
Sep 28, 2010·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Jinhua Sheng
Jan 1, 2008·IEEE Transactions on Nuclear Science·P Hendrik Pretorius, Michael A King
May 13, 2010·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Bin Zhang, Gengsheng L Zeng
Aug 12, 2005·IEEE Transactions on Medical Imaging·Yong DuEric C Frey
Jan 31, 2016·Clinical Nuclear Medicine·Kenneth James NicholsChristopher J Palestro
Aug 22, 2001·Physics in Medicine and Biology·L R BouwensR A Dierckx

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