Influence of pacing mode and rate on peripheral levels of atrial natriuretic peptide (ANP).

Pacing and Clinical Electrophysiology : PACE
B NollB Maisch

Abstract

The effect of acute modifications of pacing mode and rate on plasma ANP levels was evaluated. ANP was determined in ten resting patients with DDD pacemakers due to binodal disease or intermittent second-and third-degree AV block. At 82/minute pacing rate the ANP plasma levels (normal range 2 to 30 fmol/mL) corresponded to those under AAI (4.05 +/- 2.10 fmol/mL) and DDD (4.18 +/- 2.02 fmol/mL) pacing, but increased significantly (P 0.05) during VVI pacing (6.96 +/- 3.70 fmol/mL). Acceleration of DDD stimulation frequency from 82 to 113/minutes led to significant increase of ANP levels by the factor of three in all chosen AV delays. The lowest ANP plasma levels were measured at 175 msec AV delay under 82/minute pacing rate in DDD mode. Under 113/minutes the differences of ANP concentration after variations of AV delays were less pronounced. The influences of altered atrial pressure and tension on ANP release are discussed to account for changes in ANP plasma levels following different modes and rates of pacemaker stimulation.

References

Jul 1, 1978·The American Journal of Cardiology·C AlicandriV Morant
Mar 27, 1986·The New England Journal of Medicine·P Needleman, J E Greenwald
Nov 15, 1986·The American Journal of Cardiology·I G CrozierE A Espiner
Mar 1, 1987·Journal of the American College of Cardiology·D RoyM Cantin
Dec 1, 1986·European Journal of Clinical Investigation·W G Forssmann
Jan 1, 1987·The Journal of Clinical Endocrinology and Metabolism·M OhashiH Matsuo
Oct 1, 1980·The American Journal of Cardiology·M NaitoJ Morganroth

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Citations

Feb 1, 1995·The Annals of Thoracic Surgery·A H FosterJ S McLaughlin
Aug 1, 1992·British Heart Journal·C M Travill, R Sutton
May 1, 1992·Kidney International·D de ZeeuwP E de Jong
Aug 14, 2001·Mayo Clinic Proceedings·T C GerberD L Hayes
Sep 9, 2008·International Journal of Cardiology·Wenzhi PanJunbo Ge
Mar 15, 2002·Current Problems in Cardiology·Zalmen BlanckMasood Akhtar
Aug 1, 1990·Pacing and Clinical Electrophysiology : PACE·B NollB Maisch
Aug 30, 2000·Pacing and Clinical Electrophysiology : PACE·V Parsonnet
Jan 1, 1994·Pacing and Clinical Electrophysiology : PACE·H F ClemoK A Ellenbogen
Apr 1, 1994·Pacing and Clinical Electrophysiology : PACE·A SurdackiE Wieczorek
May 1, 1996·Pacing and Clinical Electrophysiology : PACE·J B CabelloJ A Quiles
Mar 24, 1999·Pacing and Clinical Electrophysiology : PACE·H HorieM Kinoshita
Dec 1, 1990·Pacing and Clinical Electrophysiology : PACE·G TheodorakisP Toutouzas

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