Influence of patient characteristics in the selection of patients for defibrillator implantation (the AVID Registry). Antiarrhythmics Versus Implantable Defibrillators

The American Journal of Cardiology
A B CurtisE Renfroe

Abstract

The Antiarrhythmics Versus Implantable Defibrillators (AVID) trial is a prospective, randomized study of treatment for life-threatening ventricular arrhythmias. Patients who are eligible for the main trial but who are not enrolled for any reason are followed in a registry. The objective of the present study was to determine whether there are identifiable patient characteristics among these registry patients that may influence whether a patient is treated with an implantable defibrillator. The 914 patients in the registry were divided into 2 groups according to whether the primary treatment was an implantable defibrillator. The mean age of defibrillator patients was 60 years, compared with 65 years in the nondefibrillator group (p <0.001). Only 11.2% of defibrillator recipients were minorities, whereas the percentage of minorities in the nondefibrillator group was 18.7% (p <0.003). A history of recurrent ventricular fibrillation was more likely in the group treated with defibrillators (8.9% vs 4.4%, p <0.01), whereas a history of atrial fibrillation or diabetes mellitus were both significantly more likely in the nondefibrillator group. Among defibrillator patients, a higher proportion had ventricular fibrillation as the index ar...Continue Reading

Associated Clinical Trials

References

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Citations

Feb 17, 2000·Clinical Cardiology·G V NaccarelliJ C Luck
May 4, 1999·The American Journal of Medicine·S L Pinski, G J Fahy
Aug 22, 2009·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Derek R MacFaddenDouglas S Lee
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Nov 11, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ure MezuSamir Saba
Dec 20, 2007·Cardiology in Review·Rachel Lampert
Feb 10, 2000·Current Opinion in Cardiology·G V NaccarelliJ C Luck

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