Mar 17, 1978

Influence of pindolol (Visken) on respiratory function in 20 asthmatic patients

European Journal of Clinical Pharmacology
C C ChristensenG Hansen

Abstract

The effect of a single oral dose of pindolol on bronchi was studied in a double-blind cross-over trial in 20 adult patients, most of whom had moderate bronchial asthma. A single dose of pindolol 5 mg, sufficient to cause a significant fall in heart rate and blood pressure at rest, did not produce a significant fall in the forced expiratory volume (FEV1.0). However, two patients showed marked deterioration in lung function after pindolol. A conventional therapeutic dose of salbutamol by inhalation produced a significant increase in ventilatory function relative to placebo, but it did not outweigh the bronchial effect of pindolol.

Mentioned in this Paper

Visken
Diastolic Blood Pressure
Teens
Asthma
Forced Expiratory Volume Function
Pulse Taking
Clinical Trials
Respiration
Status Asthmaticus
Double-Blind Method

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