Influence of Pneumococcal Conjugate Vaccine on Acute Otitis Media with Severe Middle Ear Inflammation: A Retrospective Multicenter Study

PloS One
Hirotoshi SuginoKatsuhiro Hirakawa

Abstract

The Japanese guidelines for acute otitis media in children recommend classifying acute otitis media by age, manifestations and local findings, and also recommend myringotomy for moderate-grade cases with severe local findings, severe-grade cases, and treatment-resistant cases. The heptavalent pneumococcal conjugate vaccine was released in Japan in February 2010. In Hiroshima City, public funding allowing free inoculation with this vaccine was initiated from January 2011, and the number of vaccinated individuals has since increased dramatically. This study investigated changes in the number of myringotomies performed to treat acute otitis media during the 5-year period from January 2008 to December 2012 at two hospitals and five clinics in the Asa Area of Hiroshima City, Japan. A total of 3,165 myringotomies for acute otitis media were performed. The rate of procedures per child-year performed in <5-year-old children decreased by 29.1% in 2011 and by 25.2% in 2012 compared to the mean rate performed in the 3 years prior to the introduction of public funding. A total of 895 myringotomies were performed for 1-year-old infants. The rate of myringotomies per child-year performed for acute otitis media in 1-year-old infants decreased...Continue Reading

References

Feb 15, 2001·The New England Journal of Medicine·J EskolaUNKNOWN Finnish Otitis Media Study Group
Jan 25, 2003·The Pediatric Infectious Disease Journal·Bruce FiremanPaula Ray
Aug 6, 2004·The Pediatric Infectious Disease Journal·Arto A I PalmuTerhi M Kilpi
Mar 7, 2007·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·Hitoshi KamiyaUNKNOWN Research Group on Streptococcus Pneumoniae Serotypes among Children
Dec 29, 2007·The Pediatric Infectious Disease Journal·Katherine L O'BrienMathuram Santosham
Oct 4, 2008·Journal of Clinical Microbiology·Muneki HotomiUNKNOWN Advanced Treatment for Otitis Media Study Group (ATOMS)
Jun 23, 2009·Epidemiology and Infection·N ChibaUNKNOWN IPD Surveillance Study Group
Jan 22, 2011·PharmacoEconomics·Chantal W B BoonackerMaroeska M Rovers
Dec 27, 2011·Auris, Nasus, Larynx·UNKNOWN Subcommittee of Clinical Practice Guideline for Diagnosis and Management of Acute Otitis Media in Children (Japan Otological
Mar 17, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sylvia TaylorMark Haggard
Nov 28, 2013·JAMA Pediatrics·Tal MaromTasnee Chonmaitree
May 26, 2015·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Kenji SuzukiHideaki Hanaki

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Citations

Feb 17, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Andrew D WieseCarlos G Grijalva
Dec 27, 2019·The Pediatric Infectious Disease Journal·Paola MarchisioElena Chiappini
Jun 30, 2021·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Masamitsu KonoMuneki Hotomi

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