PMID: 6971074Mar 1, 1981Paper

Influence of potassium cardioplegia versus ischemic arrest on regional left ventricular diastolic compliance in humans

The Annals of Thoracic Surgery
J D SlackH E McKean

Abstract

To compare the effects of hypothermic ischemic arrest versus hypothermic potassium cardioplegia, regional left ventricular performance was monitored in 20 adult male patients undergoing saphenous vein bypass operation. Twelve patients received ischemic arrest (Group 1), and 8 received potassium cardioplegia (Group 2). Groups 1 and 2 did not differ in left ventricular ejection fraction (0.62 versus 0.60), number of bypassed vessels (3.7 versus 3.4), mean cross-clamp time (75 versus 63 minutes), or mean cardiopulmonary bypass time (182 versus 170 minutes). Before cardiopulmonary bypass was begun, a pair of ultrasonic crystals was secured in the left ventricular anterior myocardium to measure segment motion and a micromanometer-tipped catheter was placed in the left ventricular chamber. All patients received a saphenous vein bypass graft to a vessel supplying the anterior left ventricular wall in the region of the ultrasonic crystals. Comparison of changes in systolic measurements revealed no significant differences between Groups 1 and 2. After saphenous vein bypass grafting, the left ventricular end-diastolic pressure (11.4 to 17.0 mm HG) and modulus of left ventricular segment stiffness (0.37 to 0.67, p less than 0.02) were ele...Continue Reading

References

Sep 1, 1979·Circulation Research·H PouleurJ W Covell
Apr 1, 1973·The Annals of Thoracic Surgery·P HairstonH B Daniell
Dec 1, 1969·Scandinavian Journal of Clinical and Laboratory Investigation·B Bugge-AsperheimF Kiil
Feb 1, 1959·Annals of Surgery·J A HELMSWORTHF K EDWARDS

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