Influence of preoperative pulmonary artery pressure on mortality after heart transplantation: testing of potential reversibility of pulmonary hypertension with nitroprusside is useful in defining a high risk group
Patients with pulmonary hypertension are at risk of developing fatal right heart failure after heart transplantation. To evaluate this risk potential, candidates for heart transplantation are screened by measuring rest right heart pressures and the response to nitroprusside. To test the validity of this approach, the influence of pretransplantation right heart catheterization data on outcome after transplantation was analyzed in 293 of 301 consecutive patients. Patients with a pulmonary vascular resistance greater than 2.5 Wood units measured at baseline study had a 3-month mortality rate of 17.9% compared with 6.9% in patients with resistance less than or equal to 2.5 units (p less than 0.02). Patients with a pulmonary vascular resistance greater than 2.5 units at baseline study could be differentiated further according to their hemodynamic response to nitroprusside; those whose resistance could be reduced to less than or equal to 2.5 units with a stable systemic systolic pressure greater than or equal to 85 mm Hg had a 3-month mortality rate of only 3.8%. In contrast, patients whose pulmonary vascular resistance could not be reduced to less than 2.5 units, and those whose resistance could be reduced to less than or equal to 2...Continue Reading
Time course of resolution of pulmonary hypertension and right ventricular remodeling after orthotopic cardiac transplantation
Potential for reversibility of pulmonary vascular obstructive disease in children after cardiac transplantation
Cardiac catheterization findings at rest and after exercise in patients following cardiac transplantation
Independence of oxygen consumption and systemic oxygen transport in patients with either stable pulmonary hypertension or refractory left ventricular failure
Successful treatment of a patient with severe pulmonary hypertension due to perivalvular leakage at aortic and mitral positions after aortic and mitral valve replacement
Pulmonary hypertension secondary to left ventricular systolic dysfunction: contemporary diagnosis and management.
Diagnosis and management of right-sided heart failure in subjects supported with left ventricular assist devices
Inhaled nitric oxide and hemodynamic evaluation of patients with pulmonary hypertension before transplantation
Post-transplant survival after lowering fixed pulmonary hypertension using left ventricular assist devices
Mild vs severe pulmonary hypertension before heart transplantation: different effects on posttransplantation pulmonary hypertension and mortality
Reversible pulmonary hypertension in heart transplant candidates does not obligatorily predict worse outcome post-transplantation
Transthoracic and transesophageal echocardiography in the hemodynamic assessment of patients with congestive heart failure
Acute reversibility of pulmonary hypertension predicts neither long-term hemodynamic response nor outcome in patients awaiting heart transplantation
Right ventricle-sparing heart transplant: promising new technique for recipients with pulmonary hypertension
Does preexisting elevated pulmonary vascular resistance (transpulmonary gradient > 15 mm Hg or > 5 wood) predict early and long-term results after orthotopic heart transplantation?
ACC expert consensus document. Present use of bedside right heart catheterization in patients with cardiac disease. American College of Cardiology
Impact of mild pulmonary hypertension on mortality and pulmonary artery pressure profile after heart transplantation
The use of milrinone in pre-transplant assessment of patients with congestive heart failure and pulmonary hypertension
Acetylcholine but not sodium nitroprusside exerts vasodilation in pulmonary hypertension secondary to chronic congestive heart failure
Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT)
Pulmonary vascular effects of nitroglycerin and isosorbide dinitrate in patients with end-stage cardiomyopathies
Initial Experience with Sildenafil, Bosentan, and Nitric Oxide for Pediatric Cardiomyopathy Patients with Elevated Pulmonary Vascular Resistance before and after Orthotopic Heart Transplantation
Determinants of ventilatory efficiency in heart failure: the role of right ventricular performance and pulmonary vascular tone.
Pulmonary vascular response patterns during exercise in left ventricular systolic dysfunction predict exercise capacity and outcomes
ULTIMATE-SHF trial (UdenafiL Therapy to Improve symptoMAtology, exercise Tolerance and hEmodynamics in patients with chronic systolic heart failure): study protocol for a randomized, placebo-controlled, double-blind trial
Clinical significance of reactive post-capillary pulmonary hypertension in patients with left heart disease
Heterotopic heart transplant: is there an indication in the continuous flow ventricular assist device era?
Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Pulmonary hypertension due to left heart disease
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