PMID: 6797997Dec 1, 1981

Influence of progesterone on arterial blood and CSF acid-base balance in women

Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
H Machida

Abstract

To study the mechanism of the action of progesterone on pulmonary ventilation during pregnancy, arterial and cerebrospinal fluid (CSF) acid-base parameters were measured in 59 pregnant and 36 nonpregnant women at the periods of follicular phase, luteal phase, early pregnancy, late pregnancy, and puerperium. Marked respiratory alkalosis in both arterial blood and CSF was observed in pregnancy and puerperium. The degree of hypocapnia observed in the luteal phase and during pregnancy was closely related to the progesterone level in arterial blood. In conclusion, it is unlikely that the observed hyperventilation results from stimulation at the central chemosensitive areas or peripheral chemoreceptors.

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Related Concepts

Menstruation
Evaluation of Acid-base Balance
Electrolytes
Lactate
Progesterone, (9 beta,10 alpha)-Isomer
Pregnancy in Diabetics
Luteal Phase
Progesterone
Cerebrospinal Fluid
Progesterone [EPC]

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