PMID: 40077Aug 1, 1979

Influence of pyloroplasty and pyloric stenosis on motoric and secretory function of the stomach after selective proximal vagotomy--an experimental study (author's transl)

Langenbecks Archiv für Chirurgie
L LehmannH D Klein


In conscious fullgrown minipigs simple SPV alone, SPV and pyloric stenosis and SPV and pyloroplasty were performed. After a liquid test meal the motoric and secretory function of the stomach were examined simultaneously by a modified method of intestinal perfusion and aspiration. After simple SPV initially a marked decrease of gastric volume and normal emptying into the duodenum were found. With additional pyloric stenosis no significant change was found. The pyloroplasty lead to an increase of gastric volume and delayed emptying. The acid secretion after feeding reduced by SPV was not changed significantly neither by pyloroplasty nor by pyloric stenosis. The baseline values of serum gastrin were elevated after SPV as well as after SPV in combination with pyloric stenosis or pyloroplasty. After food stimulation there was a delayed increase of gastrin after SPV which differed from that after SPV with pyloric stenosis or pyloroplasty only during the first hour. These results show that after SPV no further improvement of the motoric and secretory function can be achieved by an additional pyloroplasty. Furthermore these findings permit the conclusion that even after SPV with additional artificial pyloric stenosis no delayed gastric...Continue Reading


Sep 1, 1978·The British Journal of Surgery·P Aeberhard, M Walther
Mar 1, 1978·The British Journal of Surgery·J C GoligherE Nutter
Sep 1, 1978·The British Journal of Surgery·D N RalphsL P Le Quesne
Sep 1, 1977·American Journal of Surgery·C J RosenquistS Kohatsu
Jan 1, 1976·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·F Largiadèr
Apr 1, 1974·The Journal of Surgical Research·W S BattleC T Bombeck
Jan 1, 1974·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·C WastellJ I MacNaughton

Related Concepts

Pyloric Stenosis
Gastric Juice
Stenosis (invertebrate)
Entire Duodenum
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Gastrin Measurement
GAST gene

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