PMID: 15222613Jun 30, 2004Paper

Influence of recent trials on essential arterial hypertension management

La Revue du praticien
Patrick RossignolPierre-François Plouin

Abstract

Following recent trials, U.S (JNC7), European (ESH/ESC) and world (WHO) guidelines concerning the management of arterial essential hypertension have recently been updated. They indicate that hypertension treatment may succeed in preventing complications such as stroke or myocardial infarction. The therapeutic target is less than 140/90 mmHg (130/80 mmHg for diabetics). To reach this objective, a combination using a diuretic is required in almost all cases. Trials comparing the efficiency of "old drugs" such as diuretics or beta-blockers with "new drugs" such as ACEI or ARAII, or CCB observed minor differences in terms of cardiovascular outcomes. However, ACEI and ARAII appeared to be of particular efficiency in preventing heart and kidney failures.

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