Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers

The American Journal of Clinical Nutrition
María Isabel Queipo-OrtuñoFrancisco J Tinahones

Abstract

Few studies have investigated the effect of dietary polyphenols on the complex human gut microbiota, and they focused mainly on single polyphenol molecules and select bacterial populations. The objective was to evaluate the effect of a moderate intake of red wine polyphenols on select gut microbial groups implicated in host health benefits. Ten healthy male volunteers underwent a randomized, crossover, controlled intervention study. After a washout period, all of the subjects received red wine, the equivalent amount of de-alcoholized red wine, or gin for 20 d each. Total fecal DNA was submitted to polymerase chain reaction(PCR)-denaturing gradient gel electrophoresis and real-time quantitative PCR to monitor and quantify changes in fecal microbiota. Several biochemical markers were measured. The dominant bacterial composition did not remain constant over the different intake periods. Compared with baseline, the daily consumption of red wine polyphenol for 4 wk significantly increased the number of Enterococcus, Prevotella, Bacteroides, Bifidobacterium, Bacteroides uniformis, Eggerthella lenta, and Blautia coccoides-Eubacterium rectale groups (P < 0.05). In parallel, systolic and diastolic blood pressures and triglyceride, total...Continue Reading

References

Sep 1, 1995·Letters in Applied Microbiology·K TahriF Schneider
Nov 24, 1999·Journal of Agricultural and Food Chemistry·A I Romero-PérezM C de La Torre-Boronat
Apr 1, 2000·Applied and Environmental Microbiology·A BarcenillaH J Flint
Nov 20, 2002·Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan·Shuzo TaguchiShinjiro Hori
Feb 14, 2003·Lancet·Francisco Guarner, Juan-R Malagelada
Sep 27, 2003·Environmental Microbiology·James E M StachAlan T Bull
Feb 10, 2004·Applied and Environmental Microbiology·Alexandra H Smith, Roderick I Mackie
Apr 29, 2004·The American Journal of Clinical Nutrition·Claudine ManachLiliana Jiménez
Dec 3, 2004·Applied and Environmental Microbiology·Takahiro MatsukiRyuichiro Tanaka
Oct 14, 2005·Microbial Ecology·Alexandra H SmithRoderick I Mackie
May 6, 2006·Clinical Chemistry·Raul Zamora-RosCristina Andres-Lacueva
Sep 12, 2006·Research in Microbiology·Hui Cheng LeeYuan Kun Lee
Dec 16, 2006·Clinical Chemistry·Mireia Urpi-SardaCristina Andres-Lacueva
Apr 6, 2007·The New England Journal of Medicine·Kiran Musunuru, Roger S Blumenthal
Jun 21, 2007·PLoS Biology·Jian XuJeffrey I Gordon
Sep 18, 2007·Journal of the American College of Cardiology·Fadi G Hage, Alexander J Szalai
Nov 6, 2007·The British Journal of Nutrition·Xenofon TzounisJeremy P E Spencer
Jan 27, 2009·Free Radical Biology & Medicine·Raul Zamora-RosCristina Andres-Lacueva
Feb 14, 2009·Microbiological Research·Jean-Marc DelroisseDaniel Portetelle
Apr 25, 2009·Obesity·Arlette SantacruzUNKNOWN EVASYON Study Group
May 16, 2009·Current Pharmaceutical Design·Delphine M SaulnierGlenn R Gibson
Jul 2, 2009·FEMS Microbiology Letters·Carina M JungJohn B Sutherland
Jul 4, 2009·Journal of Agricultural and Food Chemistry·Timothy W SirkAmadeu K Sum
Jul 8, 2009·Journal of Agricultural and Food Chemistry·María V SelmaFrancisco A Tomás-Barberán
Dec 31, 2009·Journal of Lipid Research·Vidya R VelagapudiFredrik Bäckhed
Feb 18, 2010·FEMS Microbiology Letters·Aschalew Z BekeleYasuo Kobayashi
Jun 1, 2010·Journal of Agricultural and Food Chemistry·M Emília JuanJoana M Planas
Jan 26, 2011·Annals of the New York Academy of Sciences·Thomas Walle
Jun 29, 2011·Molecular Nutrition & Food Research·María Azorín-OrtuñoJuan C Espín
Nov 9, 2011·Journal of Agricultural and Food Chemistry·Stefano VendrameMarisa Porrini

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Citations

Apr 13, 2013·Journal of Agricultural and Food Chemistry·Ana Jiménez-GirónM Victoria Moreno-Arribas
Sep 21, 2013·Journal of Agricultural and Food Chemistry·María Boto-OrdóñezCristina Andres-Lacueva
Sep 17, 2013·Journal of Agricultural and Food Chemistry·Usune EtxeberriaMaría P Portillo
Oct 1, 2013·Journal of Agricultural and Food Chemistry·Elvira BarrosoM Carmen Martínez-Cuesta
Apr 16, 2013·BioMed Research International·Javier Rivera GuzmanChristian Jobin
Jun 3, 2014·BMC Infectious Diseases·Anne-Marie LeuckJaime S Green
Aug 1, 2014·Journal of Nutritional Science and Vitaminology·Tomonori UnnoShiho Mitsuhashi
Mar 5, 2013·Annual Review of Plant Biology·Cathie MartinKatia Petroni
Jul 3, 2013·Nutrition Reviews·Elhaseen E ElaminDaisy M Jonkers
Aug 7, 2013·Immunity & Ageing : I & a·Thea Magrone, Emilio Jirillo
Jun 12, 2013·Canadian Journal of Physiology and Pharmacology·Thea MagroneMauro Serafini
Oct 27, 2015·Biomolecules·Sheena PatelAli Keshavarzian
May 29, 2015·Nutrients·Athanasios KoutsosJulie A Lovegrove
Jan 8, 2016·Nutrients·Yoona KimPeter M Clifton
Feb 5, 2016·Alcoholism, Clinical and Experimental Research·Robin M VoigtAli Keshavarzian
Nov 26, 2015·The Journal of Antimicrobial Chemotherapy·Diego Florez-CuadradoM Concepción Porrero
Jan 1, 2014·Antioxidants·Francisco J Pérez-CanoMargarida Castell
Mar 19, 2014·The Journal of Nutritional Biochemistry·Theresa E CowanJane Shearer
Jul 16, 2013·The Journal of Nutritional Biochemistry·Fernando CardonaMaría Isabel Queipo-Ortuño
Aug 11, 2015·Molecular Nutrition & Food Research·Manuel Gómez-GuzmánJuan Duarte
Oct 9, 2012·Current Opinion in Biotechnology·Selin BolcaSam Possemiers
Jan 19, 2016·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·Joao Tomé-Carneiro, Francesco Visioli
Dec 24, 2015·Frontiers in Immunology·Stefania De SantisMarcello Chieppa
Dec 31, 2015·Biomedit︠s︡inskai︠a︡ khimii︠a︡·V B DubinkinaV M Govorun
Dec 27, 2015·Trends in Pharmacological Sciences·Liang Shen, Hong-Fang Ji
Sep 17, 2015·The Journal of Nutritional Biochemistry·Carmen HaroFrancisco Perez-Jimenez
Oct 5, 2015·Archives of Oral Biology·Elvira BarrosoTeresa Requena
Jul 23, 2014·Journal of Food Science·Gunaranjan PaturiJuliet Ansell
Mar 16, 2016·Journal of Agricultural and Food Chemistry·Xin ZhangPeifang Weng
Aug 22, 2013·Molecular Nutrition & Food Research·Hui WangMei-Jun Zhu
Oct 15, 2013·Molecular Nutrition & Food Research·María Boto-OrdóñezMireia Urpi-Sarda
Sep 2, 2015·ILAR Journal·Aaron C Ericsson, Craig L Franklin

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