Abstract
The relationship between previous exercise-induced bronchoconstriction (EIB) of different magnitude and the pulmonary response to exercise 1 h later was examined in asthmatic children. After acclimatization they performed repeated, paired exercise tests in a clean-air climatic chamber at 23 degree C. The first test of each pair was carried out in 15%, 50% and 85% relative humidity (RH), respectively, to produce different degrees of EIB. All second tests were performed in 50% RH. Changes in pulmonary function were assessed by measuring PEF and FEV1. Bronchodilatation during exercise was not influenced by RH, whereas dry air increased and humid air decreased the bronchoconstrictive response to exercise. When both tests were performed in 50% RH, the second test caused significantly less EIB than did the first test. However, no differences were found between the three second test responses. This suggests that the relative refractoriness after an episode of EIB is not related to the severity of previous bronchoconstriction, but could be associated with exercise as such or other mechanisms in EIB.
References
May 1, 1977·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·E R McFaddenJ J Wellman
Jan 1, 1976·The Journal of Allergy and Clinical Immunology·N LavinS A Kaplan
Jan 1, 1975·British Journal of Diseases of the Chest·S D AndersonS Godfrey
Aug 1, 1979·The Journal of Pediatrics·M S EdwardsC J Baker
Oct 1, 1977·British Journal of Pharmacology·D M Jackson, I M Richards
Jul 1, 1979·The Journal of Pediatrics·K H HsuG S Hsieh
Feb 1, 1978·The Journal of Clinical Investigation·R H StraussJ J Jaeger
May 1, 1978·The Journal of Pediatrics·M KattanH Levison
Sep 1, 1977·The Journal of Allergy and Clinical Immunology·O Bar-OrR Dotan
Jan 1, 1977·Respiration; International Review of Thoracic Diseases·W Y Chen, D J Horton
May 1, 1976·The Journal of Allergy and Clinical Immunology·L JamesR M Sly
Jun 1, 1972·Archives of Disease in Childhood·M Silverman, T Andrea
Nov 1, 1980·Lancet·M D Jaffe, N K Quinn
Mar 1, 1980·The Journal of Clinical Investigation·E C DealE R McFadden
Citations
Jan 1, 1984·Lung·E Bar-Yishay, S Godfrey
Nov 1, 1983·Thorax·I Ben-DovS Godfrey
Sep 1, 1995·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·G G Giesbrecht, M Younes
Jul 9, 2013·Immunology and Allergy Clinics of North America·Simon Godfrey, Kenneth D Fitch
Nov 1, 1983·American Journal of Orthodontics·A WenzelB Melsen
Jul 1, 1983·Allergy·S D Anderson
Apr 1, 1986·Allergy·J M Henriksen
Feb 1, 1997·Current Problems in Pediatrics·C Randolph
Jul 1, 1993·Respiratory Medicine·S Godfrey, E Bar-Yishay
Feb 19, 2000·Upsala Journal of Medical Sciences·L V KallingsL Bäcklund
Mar 17, 2020·Medicine and Science in Sports and Exercise·Michael George LeahyA William Sheel